Assistant Professor, Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Southwestern Medical School

Neurology

Amyn Habib is an expert in the field of Neurology. He attended Dow Medical College. Amyn Habib is also published. He has 34 publications published. The lastest publication: "The OMgp gene, a second growth suppressor within the NF1 gene.'

Publications

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• Ligand-Independent EGFR Signaling.
• DNA double-strand breaks cooperate with loss of Ink4 and Arf tumor suppressors to generate glioblastomas with frequent Met amplification.
• High expression of the stem cell marker nestin is an adverse prognostic factor in WHO grade II-III Astrocytomas and oligoAstrocytomas.
• Hippocampal sclerosis in Dementia, epilepsy, and ischemic injury: differential vulnerability of hippocampal subfields.
• Inhibition of DNA Double-Strand Break Repair by the Dual PI3K/mTOR Inhibitor NVP-BEZ235 as a Strategy for Radiosensitization of Glioblastoma.
• EGFR wild type antagonizes EGFRvIII-mediated activation of Met in glioblastoma.
• An EGFR wild type-EGFRvIII-HB-EGF feed-forward loop regulates the activation of EGFRvIII.
• Opposing Effect of EGFRWT on EGFRvIII-Mediated NF-κB Activation with RIP1 as a Cell Death Switch.
• Cytoplasmic TRADD Confers a Worse Prognosis in Glioblastoma.
• Development of a locally advanced orthotopic prostate tumor model in rats for assessment of combined modality therapy.
• Downregulation of human DAB2IP gene expression in prostate Cancer cells results in resistance to ionizing radiation.
• The receptor interacting protein 1 mediates a link between NFkappaB and PI3-kinase signaling.
• RIP1 activates PI3K-Akt via a dual mechanism involving NF-kappaB-mediated inhibition of the mTOR-S6K-IRS1 negative feedback loop and down-regulation of PTEN.
• The receptor interacting protein 1 inhibits p53 induction through NF-kappaB activation and confers a worse prognosis in glioblastoma.
• Dynamic near-infrared optical imaging of 2-deoxyglucose uptake by intracranial glioma of athymic mice.
• Differential gene expression analysis reveals generation of an autocrine loop by a mutant epidermal growth factor receptor in glioma cells.
• Oligodendrocytes regulate formation of nodes of Ranvier via the recognition molecule OMgp.
• Integrin-linked kinase is required for laminin-2-induced oligodendrocyte cell spreading and CNS myelination.
• Increased expression of epidermal growth factor receptor induces sequestration of extracellular signal-related kinases and selective attenuation of specific epidermal ...
• Constitutive and ligand-induced EGFR signalling triggers distinct and mutually exclusive downstream signalling networks.
• Expression of the oligodendrocyte-myelin glycoprotein by neurons in the mouse central Nervous system.
• The OMgp gene, a second growth suppressor within the NF1 gene.
• The epidermal growth factor receptor associates with and recruits phosphatidylinositol 3-kinase to the platelet-derived growth factor beta receptor.
• RIP1 links Inflammatory and growth factor signaling pathways by regulating expression of the EGFR.
• Epidermal growth factor receptor induced apoptosis: potentiation by inhibition of Ras signaling.
• The epidermal growth factor receptor engages receptor interacting protein and nuclear factor-kappa B (NF-kappa B)-inducing kinase to activate NF-kappa B. Identificatio...
• SNS-032 prevents hypoxia-mediated glioblastoma cell invasion by inhibiting hypoxia inducible factor-1alpha expression.
• The small-molecule CDK inhibitor, SNS-032, enhances cellular radiosensitivity in quiescent and hypoxic non-small cell lung Cancer cells.
• The death domain-containing kinase RIP1 regulates p27(Kip1) levels through the PI3K-Akt-forkhead pathway.
• SNS-032 prevents tumor cell-induced angiogenesis by inhibiting vascular endothelial growth factor.
• Improved protein arrays for quantitative Systems analysis of the dynamics of signaling pathway interactions.
• Epidermal growth factor receptor in glioma: signal transduction, neuropathology, imaging, and radioresistance.
• Loss of p15/Ink4b accompanies tumorigenesis triggered by complex DNA double-strand breaks.

Conditions Treated

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• Brain and Nervous System Cancer (incl. Gliomas, Astrocytoma, Schwannoma, Medulloblastoma, Chordoma)
• Carpal Tunnel Syndrome
• Convulsions
• Dementia
• View All

Doctors Specialties

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• Neurology

Accepted Insurances

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Education

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• University of Chicago
• Dow Medical College

Hospital

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• University of Texas Southwestern Medical Center
• Veterans Affairs North Texas Health Care System

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