Physician
Nephrology
Dr. Christine K. Abrass, MD
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Christine Abrass practices Nephrology. She attended Case Western Reserve University School of Medicine. She received awards:"Elected Member". Christine Abrass is a published physician. She has 73 publications published. The most current publication "Unique changes in interstitial extracellular matrix composition are associated with rejection and cyclosporine toxicity in human renal allograft biopsies."
Publications
- RNA-binding protein IGF2BP2/IMP2 is required for laminin-β2 mRNA translation and is modulated by glucose concentration.
- Regional Differences in Dialysis Care and Mortality among American Indians and Alaska Natives.
- De novo expression of podocyte proteins in parietal epithelial cells in experimental aging nephropathy.
- Alterations in chromatin are associated with increases in collagen III expression in aging nephropathy.
- Insulin-like growth factor-binding protein-5-induced laminin gamma1 transcription requires filamin A.
- Reductions in laminin beta2 mRNA translation are responsible for impaired IGFBP-5-mediated mesangial cell migration in the presence of high glucose.
- Laminin alpha4-null mutant mice develop Chronic kidney disease with persistent overexpression of platelet-derived growth factor.
- Rat glomerular mesangial cells require laminin-9 to migrate in Response to insulin-like growth factor binding protein-5.
- Levosimendan protects against experimental endotoxemic acute renal failure.
- IGF-1 induces rat glomerular mesangial cells to accumulate triglyceride.
- Overview: obesity: what does it have to do with Kidney disease?
- Laminin-8/9 is synthesized by rat glomerular mesangial cells and is required for PDGF-induced mesangial cell migration.
- Treatment of membranous nephropathy in the elderly.
- IGF-1-induced lipid accumulation impairs mesangial cell migration and contractile function.
- IGF-1 induces foam cell formation in rat glomerular mesangial cells.
- Clinical and antibody Responses after influenza immunization in systemic lupus erythematosus.
- Synergistic activation of the rat laminin gamma1 chain promoter by the gut-enriched Kruppel-like factor (GKLF/KLF4) and Sp1.
- Mechanisms and control of protein translation in the Kidney.
- Cellular lipid metabolism and the role of lipids in progressive renal Disease.
- Lipid metabolism and renal Disease.
- bcn-1 Element-dependent activation of the laminin gamma 1 chain gene by the cooperative action of transcription factor E3 (TFE3) and Smad proteins.
- A process for reducing workload and enhancing residents' education at an academic medical center.
- Insulin alters heterogeneous nuclear ribonucleoprotein K protein binding to DNA and RNA.
- Lupus nephritis: lessons from experimental animal models.
- Differential expression of laminin chains and anti-laminin autoantibodies in experimental lupus nephritis.
- IGFBP-5(201-218) stimulates Cdc42GAP aggregation and filopodia formationin migrating mesangial cells.
- Renal biopsy in the elderly.
- The nature of Chronic progressive nephropathy in aging rats.
- Role of laminin isoforms in glomerular structure.
- Unique changes in interstitial extracellular matrix composition are associated with rejection and cyclosporine toxicity in human renal allograft biopsies.
- Rat mesangial cells express two unique isoforms of laminin which modulate mesangial cell phenotype.
- Heparin binding domain of insulin-like growth factor binding protein-5 stimulates mesangial cell migration.
- Diabetes induces changes in glomerular development and laminin-beta 2 (s-laminin) expression.
- Clinical spectrum and complications of the nephrotic syndrome.
- Insulin-like growth factor I (IGF-I) induces unique effects in the cytoskeleton of cultured rat glomerular mesangial cells.
- Endogenous origin of glomerular endothelial and mesangial cells in grafts of embryonic Kidneys.
- Insulin induces rapid and specific rearrangement of the cytoskeleton of rat mesangial cells in vitro.
- Insulin induces a change in extracellular matrix glycoproteins synthesized by rat mesangial cells in culture.
- Aging-associated changes in renal extracellular matrix.
- Diabetes mellitus: can abnormally controlled wound healing lead to glomerulosclerosis?
- Phenotypic modulation of rat glomerular visceral epithelial cells by culture substratum.
- Diabetic nephropathy. Mechanisms of mesangial matrix expansion.
- Induction of nodular sclerosis by insulin in rat mesangial cells in vitro: studies of collagen.
- Non-specificity of circulating Immune complexes in patients with acute and chronic liver disease.
- Circulating Immune complexes in adults with idiopathic nephrotic syndrome. Collaborative Study of the Adult Idiopathic Nephrotic Syndrome.
- Correlation and predictive accuracy of circulating Immune complexes with disease activity in patients with systemic lupus erythematosus.
- Evaluation of homologous and isologous passive Heymann nephritis: influence on endogenous antibody production.
- Impaired Response of neutrophils to a lymphokine by sera from patients with connective tissue disease.
- Autologous Immune complex nephritis in rats. Influence of modification of mononuclear phagocyte system function.
- Circulating Immune complexes in rats with autologous Immune complex nephritis.
- Diabetic proteinuria. Glomerular or tubular in origin?
- Evaluation of the presence of circulating Immune complexes and their relationship to glomerular IgG deposits in streptozotocin-induced diabetic rats.
- Circulating Immune complexes in patients with diabetes mellitus.
- Therapeutic percutaneous renal artery occlusion with a detachable balloon.
- Alterations in Fc receptor function of macrophages from streptozotocin-induced diabetic rats.
- Glomerulonephritis in the elderly.
- Tamm-Horsfall protein coating of free cells in urine.
- The role of circulating antigen in the formation of Immune deposits in experimental membranous nephropathy.
- Evaluation of sequential glomerular eluates from rats with Heymann nephritis.
- Accelerated glomerulosclerosis in diabetic rats with Immune complex injury.
- Differentiation of renal from non-renal hematuria by microscopic examination of erythrocytes in urine.
- Measurement of the rates of basal pinocytosis of horseradish peroxidase and internalization of heat-aggregated IgG by macrophages from normal and streptozotocin-induce...
- Phenotypic expression of collagen types in mesangial matrix of diabetic and nondiabetic rats.
- Insulin and insulin-like growth factor I binding to cultured rat glomerular mesangial cells.
- Pathogenesis of membranous nephropathy.
- Characterization of renal injury initiated by immunization of rats with heparan sulfate.
- Alterations in plasma clearance and tissue localization of model Immune complexes in rats with streptozotocin-induced diabetes.
- Characterization of the beta-adrenergic receptor of the rat peritoneal macrophage.
- Isolation and characterization of circulating Immune complexes from rats with experimental membranous nephropathy.
- Fc-receptor-mediated phagocytosis: abnormalities associated with diabetes mellitus.
- Circulating Immune complexes in renal injury.
- Abnormal development of glomerular endothelial and mesangial cells in mice with targeted disruption of the lama3 gene.
Schools
Case Western Reserve University School of Medicine
University Of California San Diego
Mercy Hospital
Harbor UCLA Med Center
Conditions Treated
- Gout
- Hepatitis B - Immune Response
- Hypertension
- Hypertensive Heart and Chronic Kidney Disease
Doctors Specialties
- Nephrology
Accepted Insurances
Awards
- Elected Member
Education
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Harbor - UCLA Medical Center -
Scripps Mercy Hospital -
University of California San Diego -
Case Western Reserve University School of Medicine