Physician

Internal Medicine

Dr. Daniel A. Spyker, MD

Daniel Spyker practices Internal Medicine. Daniel Spyker is a published doctor. He has 95 papers published. The most current publication "Concern about safety of carotid angioplasty."

Publications

Outcomes of Patients With Premature Discontinuation of the 21-h Intravenous N-Acetylcysteine Protocol After Acute Acetaminophen Overdose.
Multiple dose pharmacokinetics of inhaled loxapine in subjects on chronic, stable antipsychotic regimens.
Effect of Smoking on the Pharmacokinetics of Inhaled Loxapine.
Safety and Tolerability of Inhaled Loxapine in Subjects with Asthma and Chronic Obstructive Pulmonary Disease-Two Randomized Controlled Trials.
Loxapine delivered as a thermally generated aerosol does not prolong QTc in a thorough QT/QTc study in healthy subjects.
The pharmacokinetics and pharmacodynamics of zaleplon delivered as a thermally generated aerosol in a single breath to volunteers.
2011 Annual report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 29th Annual Report.
Efficacy and safety of loxapine for inhalation in the treatment of agitation in patients with schizophrenia: a randomized, double-blind, placebo-controlled trial.
Amlodipine toxicity in children less than 6 years of age: a dose-response analysis using national poison data system data.
Pharmacokinetics of loxapine following inhalation of a thermally generated aerosol in healthy volunteers.
Comparison of the 20-hour intravenous and 72-hour oral acetylcysteine protocols for the treatment of acute acetaminophen poisoning.
2006 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS).
Recirculatory pharmacokinetic model of the uptake, distribution, and bioavailability of prochlorperazine administered as a thermally generated aerosol in a single brea...
Ultra-fast absorption of amorphous pure drug aerosols via deep lung inhalation.
TESS-based dose-response using pediatric clonidine exposures.
Concern about safety of carotid angioplasty.
An outbreak of pulmonary poisoning.
Commentary on 2,3,7,8-tetrachlorodibenzo-para-dioxin (TCDD).
Use of hemodialysis in meprobamate overdosage.
Intrinsic fetal circulatory dynamics by mutual impedance plethysmography.
An electrical model to simulate skin dielectric dispersion.
Subcutaneous metoclopramide in the treatment of symptomatic gastroparesis: clinical efficacy and pharmacokinetics.
Combined evidence-based literature analysis and consensus guidelines for stocking of emergency antidotes in the United States.
Oxycodone involvement in drug abuse deaths: a DAWN-based classification scheme applied to an oxycodone postmortem database containing over 1000 cases.
Assessment and reporting of clinical pharmacology information in drug labeling.
Massive overdoses with sustained-release lithium carbonate preparations: pharmacokinetic model based on two case studies.
Massive strychnine intoxication: serial blood levels in a fatal case.
Impairment of cognitive and psychomotor function by ethanol in social drinkers.
Pharmacokinetics of multiple-dose cefoperazone in hemodialysis patients.
Pharmacokinetics of amoxicillin: dose dependence after intravenous, oral, and intramuscular administration.
Pharmacokinetics of cefaclor and cephalexin: dosage nomograms for impaired renal function.
Poisoning with homatropine.
Response model analysis for cross-fostering studies: prenatal versus postnatal effects on offspring exposed to methylmercury dicyandiamide.
The acute toxicity of ethanol: dosage and kinetic nomograms.
Pharmacokinetics of amoxicillin: Dosage nomogram for patients with impaired renal function.
Pharmacokinetics of amoxicillin and ampicillin: crossover study of the effect of food.
Poisonings.
Submersion injury. Epidemiology, prevention, and management.
Activated charcoal reborn. Progress in poison management.
Sulindac hepatotoxicity: a case report and review.
Comparative single-dose pharmacokinetics of amantadine hydrochloride and rimantadine hydrochloride in young and elderly adults.
Dosage recommendations for activated charcoal-sorbitol treatment.
Activated charcoal in oral ethanol absorption: lack of effect in humans.
Neurobehavioral sequelae of subcutaneous injection with metallic mercury.
Acute amoxicillin nephrotoxicity following an overdose.
Serum osmolal gap and ethanol concentration: a simple and accurate formula.
Acute overdose with sustained release drug formulations. Perspectives in treatment.
Carbamazepine toxicity: comparison of measurement of drug levels by HPLC and EMIT and model of carbamazepine kinetics.
Toxicodynamic approach to management of the poisoned patient.
Capsicum and capsaicin--a review: case report of the use of hot peppers in child abuse.
Comparison of equal-weight oral dosages of verapamil hydrochloride and diltiazem hydrochloride in patients with mild to moderate hypertension.
Fatal transcutaneous iron intoxication.
Modulation of ethanol-induced central nervous system depression by ibuprofen.
Enhanced clearance of vancomycin by hemodialysis in a child.
What's in a name?--Regional Toxicology Treatment Centers.
Screening for disulfiram-induced liver test dysfunction in an inpatient alcoholism program.
Multiple chemical sensitivities--syndrome and solution.
Behavioral treatment of phobic avoidance in multiple chemical sensitivity.
Hemoglobin iron absorption kinetics in the iron-deficient dog.
Standardized morbidity ratios for poisonings in Virginia.
Health effects of acute carbon disulfide exposure.
Amoxapine overdose. Coma and seizures without cardiotoxic effects.
Dopamine overdosage in an infant.
Pharmacokinetics of cefaclor in renal failure: effects of multiple doses and hemodialysis.
Ethanol/ethylene glycol interaction on aca.
Age influences the clinical and serologic expression of systemic lupus erythematosus.
Differences in side effects of amantadine hydrochloride and rimantadine hydrochloride relate to differences in pharmacokinetics.
Strychnine poisoning. Recovery from profound lactic acidosis, hyperthermia, and rhabdomyolysis.
Generalized convulsions as the presenting sign of amoxapine intoxication.
Comparison of alphabetic and phonetic retrieval of online drug information.
Pharmacokinetics of aztreonam in patients with various degrees of renal dysfunction.
Yellow rain: chemical warfare in Southeast Asia and Afghanistan.
Pharmacokinetics of antimicrobial agents.
A user-oriented information system for emergency medicine.
Effect of activated charcoal in 70% sorbitol in healthy individuals.
Camphor toxicity: development of a triage strategy.
The deterrent effect of poison-warning stickers.
Pharmacokinetics of cefoperazone in normal volunteers and subjects with renal insufficiency.
Moxalactam and cefazolin: comparative pharmacokinetics in normal subjects.
Pharmacokinetics of moxalactam in subjects with various degrees of renal dysfunction.
Reduction in caffeine toxicity by acetaminophen.
Diabetes mellitus associated with autonomic and peripheral neuropathy after Vacor rodenticide poisoning: a review.
Poisoning with 4-aminopyridine: report of three cases.
An improved emergency telecommunications system for the deaf.
Computer-aided emergency telecommunications for the deaf.
Human xylazine overdose: a comparative review with clonidine, phenothiazines, and tricyclic antidepressants.
2007 Annual Report of the American Association of Poison Control Centers'' National Poison Data System (NPDS): 25th Annual Report.
The pharmacokinetics and bioavailability of prochlorperazine delivered as a thermally generated aerosol in a single breath to volunteers.
Rapid acute treatment of agitation in individuals with schizophrenia: multicentre, randomised, placebo-controlled study of inhaled loxapine.
2009 Annual Report of the American Association of Poison Control Centers'' National Poison Data System (NPDS): 27th Annual Report.
2008 Annual Report of the American Association of Poison Control Centers'' National Poison Data System (NPDS): 26th Annual Report.
Rapid acute treatment of agitation in patients with bipolar I disorder: a multicenter, randomized, placebo-controlled clinical trial with inhaled loxapine.
2010 Annual Report of the American Association of Poison Control Centers'' National Poison Data System (NPDS): 28th Annual Report.
Consistency of dosing with a thermal aerosol generation system: in vitro and in vivo correlation.

Schools

University of Virginia Main Campus

Doctors Specialties

Medical Toxicology
Internal Medicine

Accepted Insurances

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