Professor, Child Study Center, Yale University School of Medicine
Psychiatry
Dr. Flora M. Vaccarino, MD
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Flora M. Vaccarino, MD works in the field of Psychiatry. She studied medicine at University of Padua College of Medicine. Flora M. Vaccarino, MD has written publications. She has 88 publications published with PubMed. The lastest publication is: 'Development of the cerebral cortex: VII. Growth factors: II.'
Publications
- The Use of Stem Cells to Study Autism Spectrum Disorder.
- Targeted ablation of cholinergic interneurons in the dorsolateral striatum produces behavioral manifestations of Tourette syndrome.
- Editorial commentary: "What does immunology have to do with brain development and neuropsychiatric disorders?"
- Transcriptome Analysis of the Human Striatum in Tourette Syndrome.
- Leptin signaling in astrocytes regulates hypothalamic neuronal circuits and feeding.
- Neurogenesis and Maturation in Neonatal Brain Injury.
- Neurobiology of premature brain injury.
- Hypoxia-induced developmental delays of inhibitory interneurons are reversed by environmental enrichment in the postnatal mouse forebrain.
- Functional genomic screen of human stem cell differentiation reveals pathways involved in neurodevelopment and neurodegeneration.
- Cortical gyrification induced by fibroblast growth factor 2 in the mouse brain.
- Prenatal stress delays inhibitory neuron progenitor migration in the developing neocortex.
- Somatic copy number mosaicism in human skin revealed by induced pluripotent stem cells.
- Neurobiology meets genomic science: the promise of human-induced pluripotent stem cells.
- Environmental Enrichment Increases the GFAP+ Stem Cell Pool and Reverses Hypoxia-Induced Cognitive Deficits in Juvenile Mice.
- Impaired motor coordination and disrupted cerebellar architecture in Fgfr1 and Fgfr2 double knockout mice.
- Learning and Memory Depend on Fibroblast Growth Factor Receptor 2 Functioning in Hippocampus.
- FGF Signaling Expands Embryonic Cortical Surface Area by Regulating Notch-Dependent Neurogenesis.
- Cortical glial fibrillary acidic protein-positive cells generate neurons after perinatal hypoxic injury.
- Toward a novel endogenous anxiolytic factor, fibroblast growth factor 2.
- Fgfr2 is required for the development of the medial prefrontal cortex and its connections with limbic circuits.
- Decreased number of parvalbumin and cholinergic interneurons in the striatum of individuals with Tourette syndrome.
- Hypoxic injury during neonatal development in murine brain: correlation between in vivo DTI findings and behavioral assessment.
- Increased brain size in autism--what it will take to solve a mystery.
- Precursors with glial fibrillary acidic protein promoter activity transiently generate GABA interneurons in the postnatal cerebellum.
- Regulation of cerebral cortical size and neuron number by fibroblast growth factors: implications for autism.
- Fgfr1 is required for cortical regeneration and repair after perinatal hypoxia.
- Deficiency in inhibitory cortical interneurons associates with hyperactivity in fibroblast growth factor receptor 1 mutant mice.
- Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus.
- Astroglial cells in development, regeneration, and repair.
- Early postnatal astroglial cells produce multilineage precursors and neural stem cells in vivo.
- Midline radial glia translocation and corpus callosum formation require FGF signaling.
- Cortical neurogenesis enhanced by chronic perinatal hypoxia.
- Altered parvalbumin-positive neuron distribution in basal ganglia of individuals with Tourette syndrome.
- Fibroblast growth factor receptor 1 is required for the proliferation of hippocampal progenitor cells and for hippocampal growth in mouse.
- Fibroblast growth factor 2 is necessary for the growth of glutamate projection neurons in the anterior neocortex.
- Functional output of the basal forebrain.
- Self-stimulation and circling reveal functional differences between medial and lateral substantia nigra.
- Vomeronasal and olfactory system modulation of maternal behavior in the rat.
- Amygdaloid inhibition of maternal behavior in the nulliparous female rat.
- Analysis of amino acids and catecholamines, 5-hydroxytryptamine and their metabolites in brain areas in the rat using in vivo microdialysis.
- In vivo modulation of brain dopamine recognition sites: a possible model for emission computed tomography studies.
- Neuroendocrine function and response to stress in mice with complete disruption of glucagon-like peptide-1 receptor signaling.
- Development of the cerebral cortex: VII. Growth factors: II.
- Pyramidal neurons are generated from oligodendroglial progenitor cells in adult piriform cortex.
- Subcellular location and neuronal release of diazepam binding inhibitor.
- GABAergic synapses. Supramolecular organization and biochemical regulation.
- Otx2 regulates subtype specification and neurogenesis in the midbrain.
- gamma-Aminobutyric acid- and benzodiazepine-induced modulation of [35S]-t-butylbicyclophosphorothionate binding to cerebellar granule cells.
- GABA-modulin: a synaptosomal basic protein that differs from small myelin basic protein of rat brain.
- Astroglial cells in the external granular layer are precursors of cerebellar granule neurons in neonates.
- Chronic neonatal hypoxia leads to long term decreases in the volume and cell number of the rat cerebral cortex.
- Loss of glutamatergic pyramidal neurons in frontal and temporal cortex resulting from attenuation of FGFR1 signaling is associated with spontaneous hyperactivity in mice.
- Ganglioside inhibition of glutamate-mediated protein kinase C translocation in primary cultures of cerebellar neurons.
- Subsets of GABAergic neurons in dissociated cell cultures of neonatal rat cerebral cortex show co-localization with specific modulator peptides.
- Loss of Purkinje cell-associated benzodiazepine receptors spares a high affinity subpopulation: a study with pcd mutant mice.
- Modulation of gamma-aminobutyric acid-mediated inhibitory synaptic currents in dissociated cortical cell cultures.
- Coexistence of GABA receptors and GABA-modulin in primary cultures of rat cerebellar granule cells.
- Residual benzodiazepine (BZ) binding in the cortex of pcd mutant cerebella and qualitative BZ binding in the deep cerebellar nuclei of control and mutant mice: an auto...
- Glutamate receptors, protein kinase C translocation, and gangliosides.
- Primary cultures of corticostriatal cells from newborn rats: a model to study muscarinic receptor subtypes regulation and function.
- Modulation of protein kinase C translocation by excitatory and inhibitory amino acids in primary cultures of neurons.
- Differential induction of immediate early genes by excitatory amino acid receptor types in primary cultures of cortical and striatal neurons.
- Progressive impairment of developing neuroendocrine cell lineages in the hypothalamus of mice lacking the Orthopedia gene.
- Identification, chromosomal assignment, and expression analysis of the human homeodomain-containing gene Orthopedia (OTP).
- Fibroblast growth factor signaling regulates growth and morphogenesis at multiple steps during brain development.
- Changes in cerebral cortex size are governed by fibroblast growth factor during embryogenesis.
- Dlx-2 homeobox gene controls neuronal differentiation in primary cultures of developing basal ganglia.
- Characterization and sequence analysis of the human homeobox-containing gene GBX2.
- Fibroblast growth factor 2 increases Otx2 expression in precursor cells from mammalian telencephalon.
- Induction of immediate early genes by cyclic AMP in primary cultures of neurons from rat cerebral cortex.
- Excitatory amino acid receptors in glial progenitor cells: molecular and functional properties.
- Basic fibroblast growth factor increases the number of excitatory neurons containing glutamate in the cerebral cortex.
- The subcellular localization of Otx2 is cell-type specific and developmentally regulated in the mouse retina.
- Basic fibroblast growth factor (Fgf2) is necessary for cell proliferation and neurogenesis in the developing cerebral cortex.
- Chronic hypoxia up-regulates fibroblast growth factor ligands in the perinatal brain and induces fibroblast growth factor-responsive radial glial cells in the sub-epen...
- Injury and repair in developing brain.
- Stem cells in neurodevelopment and plasticity.
- Modeling thought and feelings: the why, what and whereabouts of animals in psychiatry.
- Fibroblast growth factor 2 is required for maintaining the neural stem cell pool in the mouse brain subventricular zone.
- Decrease in excitatory neurons, astrocytes and proliferating progenitors in the cerebral cortex of mice lacking exon 3 from the Fgf2 gene.
- Modeling premature brain injury and recovery.
- Exciting news from the adult mouse subventricular zone.
- Annotation: Tourette syndrome: a relentless drumbeat--driven by misguided brain oscillations.
- Annual Research Review: The promise of stem cell research for neuropsychiatric disorders.
- Neural stem cell regulation, fibroblast growth factors, and the developmental origins of neuropsychiatric disorders.
- Induced pluripotent stem cells: a new tool to confront the challenge of neuropsychiatric disorders.
- Kv3.3 Channels Bind Hax-1 and Arp2/3 to Assemble a Stable Local Actin Network that Regulates Channel Gating.
Doctors Specialties
- Psychiatry
Accepted Insurances
Education
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Yale New Haven Children's Center -
University of Padua College of Medicine
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