Associate Professor, Internal Medicine, University of Iowa College of Medicine Vice-Chair for Research Dept. of Internal Medicine Chief, Cardiology Iowa City VA Healthcare System
Cardiology
Dr. Isabella M. Grumbach, MD
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Dr. Isabella M. Grumbach is an expert in the field of Cardiology. Isabella Grumbach is also published. He has 40 publications published. The lastest publication: "Low prevalence of hepatitis C virus antibodies and RNA in patients with myocarditis and dilated cardiomyopathy.' Isabella Grumbach accepts all Medicare patients.
Publications
- Fibronectin Splicing Variants Containing Extra Domain A Promote Atherosclerosis in Mice Through Toll-Like Receptor 4.
- CaMKII inhibition in Type II pneumocytes protects from bleomycin-induced Pulmonary fibrosis by preventing Ca2+-dependent apoptosis.
- Mitochondrial-targeted Antioxidant Therapy Decreases TGFβ Mediated Collagen Production in a Murine Asthma Model.
- Oxidative activation of the Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) regulates vascular smooth muscle migration and apoptosis.
- Differential Control of Calcium Homeostasis and Vascular Reactivity by Ca2+/Calmodulin-Dependent Kinase II.
- CaMKII is essential for the proasthmatic effects of oxidation.
- The multifunctional Ca2+/calmodulin-dependent kinase II (CaMKII) regulates vascular smooth muscle migration through matrix metalloproteinase 9 (MMP9).
- Sildenafil Prevents and Reverses Transverse-Tubule Remodeling and Ca2+ Handling Dysfunction in Right Ventricle Failure Induced by Pulmonary Artery Hypertension.
- Oxidation of CaMKII determines the cardiotoxic effects of aldosterone.
- Oxidized CaMKII causes cardiac sinus node dysfunction in mice.
- CaMKII in the Cardiovascular System: Sensing Redox States.
- The multifunctional Ca2+/calmodulin-dependent kinase II delta (CaMKIIdelta) controls neointima formation after Carotid ligation and vascular smooth muscle cell prolife...
- CaV1.2 beta-subunit coordinates CaMKII-triggered cardiomyocyte death and afterdepolarizations.
- Calmodulin kinase II is required for angiotensin II-mediated vascular smooth muscle hypertrophy.
- Calmodulin kinase II is required for fight or flight sinoAtrial node physiology.
- Shear stress regulates endothelial nitric-oxide synthase promoter activity through nuclear factor kappaB binding.
- The multifunctional Ca(2)(+)/calmodulin-dependent kinase IIdelta (CaMKIIdelta) regulates arteriogenesis in a mouse model of flow-mediated remodeling.
- Giant cell myocarditis due to coxsackie B2 virus infection.
- Immunohistochemical localization of five members of the Kv1 channel subunits: contrasting subcellular locations and neuron-specific co-localizations in rat brain.
- The SA/rABC technique: a new ABC procedure for detection of antigens at increased sensitivity.
- Sulpho-N-hydroxysuccinimide activated long chain biotin. A new microtitre plate assay for the determination of its stability at different pH values and its reaction ra...
- The p38 MAPK pathway mediates the growth inhibitory effects of interferon-alpha in BCR-ABL-expressing cells.
- Engagement of the CrkL adaptor in interferon alpha signalling in BCR-ABL-expressing cells.
- Transient induction of cytokine production in human Myocardial fibroblasts by coxsackievirus B3.
- Activation of the Jak-Stat pathway in cells that exhibit selective sensitivity to the antiviral effects of IFN-beta compared with IFN-alpha.
- Adenoviruses and enteroviruses as pathogens in myocarditis and dilated Cardiomyopathy.
- Low prevalence of hepatitis C virus antibodies and RNA in patients with myocarditis and dilated Cardiomyopathy.
- [Percutaneous balloon pericardiotomy for the treatment of a malignant Pericardial tamponade].
- Coxsackievirus genome in myocardium of patients with arrhythmogenic right ventricular dysplasia/Cardiomyopathy.
- Interferon alpha activates the tyrosine kinase Lyn in haemopoietic cells.
- Monocyte activation in congestive heart failure due to Coronary artery disease and idiopathic dilated cardiomyopathy.
- Highly sensitive detection of gene expression of an intronless gene: amplification of mRNA, but not genomic DNA by nucleic acid sequence based amplification (NASBA).
- Antiviral activity of WIN 54954 in coxsackievirus B2 carrier state infected human Myocardial fibroblasts.
- Detection of enterovirus RNA in the myocardium of a patient with arrhythmogenic right ventricular Cardiomyopathy by in situ hybridization.
- Enterovirus heart Disease of adults: a persistent, limited organ infection in the presence of neutralizing antibodies.
- Inhibition of coxsackievirus B3 carrier state infection of cultured human Myocardial fibroblasts by ribavirin and human natural interferon-alpha.
- Recombinant Interferons beta and gamma have a higher antiviral activity than interferon-alpha in coxsackievirus B3-infected carrier state cultures of human Myocardial ...
- Endothelial mechanotransduction, nitric oxide and vascular inflammation.
- A negative feedback mechanism involving nitric oxide and nuclear factor kappa-B modulates endothelial nitric oxide synthase transcription.
Procedures Preformed
- Ablation for Treatment of Cardiac Arrhythmias
- Cardiac Catheterization (incl. Coronary Angiography)
- Cardiac Imaging
- Cardiac MRI (Magnetic Resonance Imaging) of Heart or Chest
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Conditions Treated
- Angina and Acute Coronary Syndrome
- Aortic Aneurysm
- Aortic Ectasia
- Aortic Valve Disease
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Doctors Specialties
- Cardiology
Accepted Insurances
- Choice Plus POS II
- American Republic
- Assurant Health
- Blue Card PPO
- Blue Cross Blue Shield of Illinois PPO
- Cigna PPO
- Great West Healthcare-Cigna PPO
- Open Access Plus
- Commercial Insurance Company
- CoreSource
- Coventry Health Care
- First Health (Coventry Health Care) PPO
- GEHA
- Choice Care PPO
- Mail Handlers Benefit Plan (MHBP)
- Medicare MCR
- Medico
- Meritain Health
- Mutual of Omaha
- Principal Life
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
- United Healthcare
- Alliance Select
Education
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Emory University -
John H. Stroger Hospital of Cook County -
Ruhr- University Bochum Faculty of Medicine
Drug Facts
| NPI NUMBER | 1730108879 | |
| NPPES Provider LastName | GRUMBACH | |
| NPPES Provider FirstName | ISABELLA | |
| NPPES Provider ZIPCode | 522421009 | |
| NPPES Provider State | IA | |
| Specialty Description | Cardiology | |
| Total Claim Count | 11.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1730108879 |
| Last Name Of The Provider | GRUMBACH |
| First Name Of The Provider | ISABELLA |
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