Professor of Medicine, Medical College VA
Endocrinology
Dr. John E. Nestler, MD
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John Nestler is an expert in the field of Endocrinology. He went to Perelman School of Medicine at the University of Pennsylvania. He received awards:"America's Top Doctors" and "Elected Member". John Nestler is also published. He has 100 publications published. The lastest publication: "Polycystic ovary syndrome: a disorder for the generalist.' He accepts Medicare payments and is listed with Medicare.gov.
Publications
- Polycystic ovary syndrome and insulin: our understanding in the past, present and future.
- Smoking in infertile women with polycystic ovary syndrome: baseline validation of self-report and effects on phenoType.
- Activation of the LH receptor up regulates the Type 2 adiponectin receptor in human granulosa cells.
- A pilot study: effects of decreasing serum insulin with diazoxide on vitamin D levels in obese women with Polycystic ovary syndrome.
- Cardiometabolic Aspects of the Polycystic Ovary Syndrome.
- Sex hormone-binding globulin and type 2 Diabetes mellitus.
- Effect of combined metformin and oral contraceptive therapy on metabolic factors and endothelial function in overweight and obese women with Polycystic ovary syndrome.
- Divergent effects of a combined hormonal oral contraceptive on insulin sensitivity in lean versus obese women.
- Polymorphisms in the SHBG Gene Influence Serum SHBG Levels in Women with Polycystic Ovary Syndrome.
- Total and high-molecular weight adiponectin in women with the Polycystic ovary syndrome.
- Uncoupling between insulin and release of a D-chiro-inositol-containing inositolphosphoglycan mediator of insulin action in obese women With Polycystic ovary syndrome.
- Sex hormone-binding globulin and risk of type 2 Diabetes.
- Risk of cardiovascular events in mothers of women with Polycystic ovary syndrome.
- Insulin-stimulated release of D-chiro-inositol-containing inositolphosphoglycan mediator correlates with insulin sensitivity in women with Polycystic ovary syndrome.
- Metformin in the treatment of infertility in Polycystic ovarian syndrome: an alternative perspective.
- Glucose intolerance in Polycystic ovary syndrome--a position statement of the Androgen Excess Society.
- Leptin secretory burst mass correlates with body mass index and insulin in normal women but not in women with Polycystic ovary syndrome.
- Effect of macronutrient composition on postprandial peptide YY levels.
- Lack of effect of short-term diazoxide administration on luteinizing hormone secretion in women with Polycystic ovary syndrome.
- Changes in glucose tolerance with metformin treatment in Polycystic ovary syndrome: a retrospective analysis.
- The metabolic syndrome in Polycystic ovary syndrome.
- Effects of short-term and long-term metformin treatment on menstrual cyclicity in women with Polycystic ovary syndrome.
- Metabolic syndrome in women with Polycystic ovary syndrome.
- Dermatology of androgen-related Disorders.
- Fertility in Polycystic ovary syndrome.
- Altered D-chiro-inositol urinary clearance in women with Polycystic ovary syndrome.
- Commentary: Polycystic ovary syndrome: a syndrome of ovarian hypersensitivity to insulin?
- Association between the current use of low-dose oral contraceptives and cardiovascular arterial disease: a meta-analysis.
- Prevalence and characteristics of the metabolic syndrome in women with Polycystic ovary syndrome.
- Effects of metformin and rosiglitazone, alone and in combination, in nonobese women with Polycystic ovary syndrome and normal indices of insulin sensitivity.
- Reduced serum glycodelin and insulin-like growth factor-binding protein-1 in women with Polycystic ovary syndrome during first trimester of pregnancy.
- Metformin therapy increases insulin-stimulated release of D-chiro-inositol-containing inositolphosphoglycan mediator in women with Polycystic ovary syndrome.
- Insulin resistance syndrome and Polycystic ovary syndrome.
- Insulin sensitizers for Polycystic ovary syndrome.
- A modern medical quandary: Polycystic ovary syndrome, insulin resistance, and oral contraceptive pills.
- Effects of d-chiro-inositol in lean women with the Polycystic ovary syndrome.
- Genetic covariation between serum gamma-glutamyltransferase activity and cardiovascular risk factors.
- Strategies for the use of insulin-sensitizing drugs to treat infertility in women with Polycystic ovary syndrome.
- Effects of metformin on early pregnancy loss in the Polycystic ovary syndrome.
- Genetics of serum dehydroepiandrosterone sulfate and its relationship to insulin in a population-based cohort of twin subjects.
- Tissue distribution of hantavirus antigen in naturally infected humans and deer mice.
- Diclofenac-associated hepatotoxicity.
- [Streptococcus-induced Syndrome of toxic shock (streptococcal toxic shock Syndrome)].
- A pilot study of social competence group training for adolescents with borderline intellectual functioning and emotional and behavioural problems (SCT-ABI).
- Fish migration, dams, and loss of ecosystem services in the Mekong basin.
- Prevalence of polycystic ovary syndrome among premenopausal women with type 2 Diabetes.
- Insulin-lowering drugs in Polycystic ovary syndrome.
- Metformin and the Polycystic ovary syndrome.
- Insulin reduction with metformin increases luteal phase serum glycodelin and insulin-like growth factor-binding protein 1 concentrations and enhances uterine vasculari...
- The Polycystic ovary syndrome: treatment with insulin sensitizing agents.
- Metformin increases the ovulatory rate and pregnancy rate from clomiphene citrate in patients with Polycystic ovary syndrome who are resistant to clomiphene citrate al...
- Role of inositolphosphoglycan mediators of insulin action in the Polycystic ovary syndrome.
- Obesity, insulin, sex steroids and ovulation.
- The effect of dehydroepiandrosterone supplementation to symptomatic perimenopausal women on serum endocrine profiles, Lipid parameters, and health-related quality of l...
- Ovulatory and metabolic effects of D-chiro-inositol in the Polycystic ovary syndrome.
- Inositolphosphoglycans (IPGs) as mediators of insulin's steroidogenic actions.
- Polycystic ovary syndrome: a disorder for the generalist.
- Effects of metformin on spontaneous and clomiphene-induced ovulation in the Polycystic ovary syndrome.
- Insulin stimulates testosterone biosynthesis by human thecal cells from women with Polycystic ovary syndrome by activating its own receptor and using inositolglycan me...
- Evaluation and treatment of the hirsute woman.
- The central role of Obesity (hyperinsulinemia) in the pathogenesis of the polycystic ovary syndrome.
- Sleep-associated fall in glucose disposal and hepatic glucose output in normal humans. Putative signaling mechanism linking peripheral and hepatic events.
- Morning insulin requirements. Critique of dawn and meal phenomena.
- Insulin and insulin-like growth factor-I stimulate the 3 beta-hydroxysteroid dehydrogenase activity of human placental cytotrophoblasts.
- Lack of effect of insulin or insulin-like growth factor I on the steroid sulfatase activity of human placental cytotrophoblasts.
- Suppression of serum dehydroepiandrosterone sulfate levels by insulin: an evaluation of possible mechanisms.
- Suppression of serum insulin by diazoxide reduces serum testosterone levels in obese women with Polycystic ovary syndrome.
- Insulin-like growth factor II is a potent inhibitor of the aromatase activity of human placental cytotrophoblasts.
- Suppression of serum insulin level by diazoxide does not alter serum testosterone or sex hormone-binding globulin levels in healthy, nonobese women.
- Increased transcapillary escape rate of albumin in nondiabetic men in response to hyperinsulinemia.
- Impaired modulation of hepatic glucose output overnight after a 72-h fast in normal man.
- Lack of effect of dehydroepiandrosterone in obese men.
- Insulin mediators are the signal transduction system responsible for insulin's actions on human placental steroidogenesis.
- In vivo evidence for hepatic autoregulation during FFA-stimulated gluconeogenesis in normal humans.
- A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with the Polycystic ovary syndrome.
- Evidence for dual control mechanism regulating hepatic glucose output in nondiabetic men.
- Metabolism and actions of dehydroepiandrosterone in humans.
- Insulin as an effector of human ovarian and adrenal steroid Metabolism.
- Evidence for increased liver glycogen in patients with noninsulin-dependent Diabetes mellitus after a 3-day fast.
- Insulin inhibits adrenal 17,20-lyase activity in man.
- Interleukin-1 is induced in the human placenta by endotoxin and isolation procedures for trophoblasts.
- Diabetes and adrenal disease.
- Dehydroepiandrosterone: the "missing link" between hyperinsulinemia and atherosclerosis?
- Insulin regulation of human Ovarian androgens.
- Lean women with Polycystic ovary syndrome respond to insulin reduction with decreases in ovarian P450c17 alpha activity and serum androgens.
- Role of hyperinsulinemia in the pathogenesis of the Polycystic ovary syndrome, and its clinical implications.
- Effect of insulin on serum levels of dehydroepiandrosterone metabolites in men.
- 17 alpha-Hydroxyprogesterone responses to leuprolide and serum androgens in obese women with and without Polycystic ovary syndrome offer dietary weight loss.
- Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in Polycystic ovary syndrome.
- Dehydroepiandrosterone reduces plasma plasminogen activator inhibitor Type 1 and tissue plasminogen activator antigen in men.
- Regulation of human dehydroepiandrosterone Metabolism by insulin.
- Dehydroepiandrosterone inhibits human platelet aggregation in vitro and in vivo.
- The Calcium channel blocker amlodipine raises serum dehydroepiandrosterone sulfate and androstenedione, but lowers serum cortisol, in insulin-resistant obese and hyper...
- Sites of inhibition of steroidogenesis by activation of protein kinase-C in swine Ovarian (granulosa) cells.
- Regulation of the aromatase activity of human placental cytotrophoblasts by insulin, insulin-like growth factor-I, and -II.
- Relation of adrenal androgen to insulin levels.
- Sex hormone-binding globulin: a marker for hyperinsulinemia and/or insulin resistance?
- Interleukin-1 stimulates the aromatase activity of human placental cytotrophoblasts.
- Effects of nitrendipine on glucose tolerance and serum insulin and dehydroepiandrosterone sulfate levels in insulin-resistant obese and hypertensive men.
Schools
Univ Of Pa Sch Of Med
Med College Va
University Of Pennsylvania
Conditions Treated
- Calcium Metabolism Disorders
- Craniopharyngioma
- Diabetes Type 2
- Goiter
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Doctors Specialties
- Endocrinology
Accepted Insurances
Awards
- America's Top Doctors
- Elected Member
Education
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Virginia Commonwealth University Health System -
University of Pennsylvania Health System -
Perelman School of Medicine at the University of Pennsylvania
Drug Facts
| NPI NUMBER | 1639269285 | |
| NPPES Provider LastName | NESTLER | |
| NPPES Provider FirstName | JOHN | |
| NPPES Provider ZIPCode | 232985051 | |
| NPPES Provider State | VA | |
| Specialty Description | Endocrinology | |
| Total Claim Count | 66.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1639269285 |
| Last Name Of The Provider | NESTLER |
| First Name Of The Provider | JOHN |
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