Associate Professor, Pediatrics, University of Utah School of Medicine
Pediatric Hematology & Oncology
Dr. Nikolaus S. Trede, MD
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Dr. Nikolaus S. Trede is an expert in the field of Pediatric Hematology & Oncology. Doctor Nikolaus S. Trede, MD has written publications. He has 56 publications published with PubMed. The lastest publication is: 'Development of T-cells during fish embryogenesis.'
Publications
- VPREB1 deletions occur independent of lambda light chain rearrangement in childhood Acute lymphoblastic leukemia.
- Ribosomal protein SA haploinsufficiency in humans with isolated congenital asplenia.
- Discovery of Biologically Active Oncologic and Immunologic Small Molecule Therapies using Zebrafish: Overview and Example of Modulation of T Cell Activation.
- Genomic Amplification of an Endogenous Retrovirus in Zebrafish T-Cell Malignancies.
- Tbl3 regulates cell cycle length during zebrafish development.
- Zebrafish screen identifies novel compound with selective toxicity against Leukemia.
- Human T cell expansion and experimental autoimmune encephalomyelitis inhibited by Lenaldekar, a small molecule discovered in a zebrafish screen.
- Trans-centromere effects on meiotic recombination in the zebrafish.
- Characterization of the zebrafish T cell receptor beta locus.
- Disease modeling in zebrafish: Cancer and immune responses--a report on a workshop held in Spoleto, Italy, July 20-22, 2009.
- The role and regulation of friend of GATA-1 (FOG-1) during blood development in the zebrafish.
- Mutations affecting the secretory COPII coat component SEC23B cause congenital dyserythropoietic Anemia type II.
- Zebrafish mutants with disrupted early T-cell and thymus development identified in early pressure screen.
- Evolutionarily conserved and divergent regions of the autoimmune regulator (Aire) gene: a comparative analysis.
- Immunology and zebrafish: spawning new models of human disease.
- Network of coregulated spliceosome components revealed by zebrafish mutant in recycling factor p110.
- Resolution of the novel immune-type receptor gene cluster in zebrafish.
- The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis.
- In vivo tracking of T cell development, ablation, and engraftment in transgenic zebrafish.
- Cloning and characterization of an Mx gene and its corresponding promoter from the zebrafish, Danio rerio.
- The use of zebrafish to understand immunity.
- Cell-specific mitotic defect and dyserythropoiesis associated with erythroid band 3 deficiency.
- Myc-induced T cell Leukemia in transgenic zebrafish.
- The zebrafish as a model organism to study development of the immune system.
- Successful antiangiogenic therapy of giant cell angioblastoma with interferon alfa 2b: report of 2 cases.
- Targeting insulin-like growth factor 1 leads to amelioration of inflammatory demyelinating disease.
- Fish immunology.
- The zebrafish as a model for Cancer.
- A model 450 million years in the making: zebrafish and vertebrate immunity.
- Shared acquired genomic changes in zebrafish and human T-ALL.
- The improvised atraumatic suture: a cost-reducing technique, not only for the tropics?
- Fishing for lymphoid genes.
- Development of T-cells during fish embryogenesis.
- Tacrolimus (FK506) in allogeneic bone marrow transplantation for severe aplastic Anemia following orthotopic liver transplantation.
- Microbial superantigens induce NF-kappa B in the human monocytic cell line THP-1.
- Activator protein-1 (AP-1) is stimulated by microbial superantigens in human monocytic cells.
- Early activation events induced by the staphylococcal superantigen toxic shock syndrome toxin-1 in human peripheral blood monocytes.
- Superantigens activate HIV-1 gene expression in monocytic cells.
- Transcriptional activation of the human TNF-alpha promoter by superantigen in human monocytic cells: role of NF-kappa B.
- Serological screening for allergy to inhalants by multi-allergen-radioimmunoassay.
- [Oral hyposensitization].
- Combination of parenteral and oral immunotherapy in grass pollen-allergic children. A double-blind controlled study of clinical and immunological efficacy.
- Different large deletions of T cell receptor V beta genes in natural populations of mice.
- Complexity, polymorphism, and recombination of mouse T-cell receptor alpha gene families.
- Transcriptional activation of IL-1 beta and tumor necrosis factor-alpha genes by MHC class II ligands.
- Toxic shock syndrome toxin-1, toxic shock, and the immune system.
- Role of protein tyrosine phosphorylation in monokine induction by the staphylococcal superantigen toxic shock syndrome toxin-1.
- Cellular and molecular mechanisms of immune activation by microbial superantigens: studies using toxic shock syndrome toxin-1.
- Non-cell autonomous requirement for the bloodless gene in primitive hematopoiesis of zebrafish.
- Method for isolation of PCR-ready genomic DNA from zebrafish tissues.
- Heritable T-cell malignancy models established in a zebrafish phenotypic screen.
- Enhanced transcription of complement and Coagulation genes in the absence of adaptive immunity.
- Mitoferrin is essential for erythroid iron assimilation.
- Model systems for infectious disease and Cancer in zebrafish: a report on an EMBO workshop held at the Lorentz Center, Leiden, The Netherlands, July 16-18, 2007.
- Alcama mediates Edn1 signaling during zebrafish cartilage morphogenesis.
Conditions Treated
- Acute Leukemia
- Anemia
- Coagulation Disorders (incl. Hemophilia)
- Liver Cancer
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Doctors Specialties
- Pediatric Hematology
- Oncology
Accepted Insurances
Education
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Boston Children's Hospital -
Albert Ludwigs University Faculty of Medicine
Hospital
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University of Utah Health Care - Hospital and Clinics
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