William H. Eilinger Professor and Chair, Department of Pediatrics; Professor, Departments of Neurology and Neurobiology and Anatomy, University of Rochester Medical Center
Pediatrics
Dr. Nina F. Schor, MD
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Nina F. Schor works in the field of Pediatrics. She went to Weill Cornell Medical College of Cornell University. Weill Cornell Medical College of Cornell University is ranked 18/49 in Research/PrimaryCare. She over the years received 1 awards: "Top MD". Nina Schor is also a published MD. She has 100 publication published. The most recent publication is: Glutamate-induced cytotoxicity in PC12 pheochromocytoma cells: role of oxidation of phospholipids, glutathione and protein sulfhydryls revealed by bcl-2 transfection.
Publications
- Kidins220/ARMS is expressed in neuroblastoma tumors and stabilizes neurotrophic signaling in a human neuroblastoma cell line.
- p75 neurotrophin receptor and fenretinide-induced signaling in neuroblastoma.
- Introductory address for the John Howland Award recipient, Elizabeth R. McAnarney, MD.
- Why our patients (and we) need basic science research.
- Aiming at Neuroblastoma and Hitting Other Worthy Targets.
- Life at the interface: Adults with "pediatric" disorders of the nervous system.
- Kidins220/ARMS depletion is associated with the neural-to Schwann-like transition in a human neuroblastoma cell line model.
- p75NTR: an enhancer of fenretinide toxicity in neuroblastoma.
- Anticipatory Guidance as a Principle of Faculty Development: Managing Transition and Change.
- Pediatric residency preceding child neurology training.
- Necdin and neurotrophin receptors: interactors of relevance for neuronal resistance to oxidant stress.
- What the halted phase III γ-secretase inhibitor trial may (or may not) be telling us.
- Chopper Is Prodeath Regardless of the Effect of p75ICD on Sensitivity to Oxidative Stress.
- The endoplasmic reticulum stress response factor CHOP-10 protects against hypoxia-induced neuronal death.
- The child is father to the man: developmental roles for proteins of importance for neurodegenerative disease.
- Reflections: neurology and the humanities. Prayer (dement me not).
- Necdin and TrkA contribute to modulation by p75NTR of resistance to oxidant stress.
- Role of tyrosine phosphorylation in the antioxidant effects of the p75 neurotrophin receptor.
- Reflections: neurology and the humanities. Developmental arrest.
- Resident work hours: isolating one ledger column and missing the point.
- Loss of c/EBP-beta activity promotes the adaptive to apoptotic switch in hypoxic cortical neurons.
- Expression and p75 neurotrophin receptor dependence of cholesterol synthetic enzymes in adult mouse brain.
- p75NTR enhances PC12 cell tumor growth by a non-receptor mechanism involving downregulation of cyclin D2.
- Child neurology: a trilogy.
- Brain Mets: a poem in three voices.
- P75 neurotrophin receptor regulates expression of neural cell adhesion molecule 1.
- Transcriptome differences between the frontal cortex and hippocampus of wild-type and humanized presenilin-1 transgenic mice.
- The Scholarly Project Initiative: introducing scholarship in medicine through a longitudinal, mentored curricular program.
- Treatment with propofol: the new status quo for status epilepticus?
- Presenilin-1-dependent transcriptome changes.
- Toward the definition of acute disseminated encephalitis of childhood.
- Effects of pH on the cytotoxicity of sodium trioxodinitrate (Angeli's salt).
- Brain imaging and prophylactic therapy in children with migraine: recommendations versus reality.
- The supportive academic environment: ingredients for success.
- Formation of nitroxyl and hydroxyl radical in solutions of sodium trioxodinitrate: effects of pH and cytotoxicity.
- Building a division of child neurology: a tribute to Michael J. Painter, MD.
- TrkA as a life and death receptor: receptor dose as a mediator of function.
- p75-nerve growth factor as an antiapoptotic complex: independence versus cooperativity in protection from enediyne chemotherapeutic agents.
- Role of caspase 3-dependent Bcl-2 cleavage in potentiation of apoptosis by Bcl-2.
- Cell Line-Dependent Variability of Coordinate Expression of p75NTR and CRABP1 and Modulation of Effects of Fenretinide on Neuroblastoma Cells.
- Cerebellar glutamine synthetase in children after hypoxia or ischemia.
- Determinants of the response of neuroblastoma cells to DNA damage: the roles of pre-treatment cell morphology and chemical nature of the damage.
- Structural studies on the inactivation of gamma-glutamylcysteine synthetase by the disulphide analogues of radioprotective cysteamine derivatives. Effects of aminoalky...
- Inactivation of gamma-glutamylcysteine synthetase by SAPH-3 disulfide: role of the histaminyl moiety.
- Neuroblastoma as a neurobiological disease.
- Bobble-head doll syndrome and drop attacks in a child with a cystic choroid plexus papilloma of the third ventricle. Case report.
- Induction of apoptosis in murine and human neuroblastoma cell lines by the enediyne natural product neocarzinostatin.
- Nervous system dysfunction in children with paraneoplastic syndromes.
- Neocarzinostatin induces neuronal morphology of mouse neuroblastoma in culture.
- Depletion of glutathione by the radioprotective agent S-2-(3-aminopropylamino)ethyl phosphorothioic acid (WR2721).
- Targeted enhancement of the biological activity of the antineoplastic agent, neocarzinostatin. Studies in murine neuroblastoma cells.
- Effect of inclusion of cost information on student and faculty evaluation of a computer-assisted, problem-based learning course.
- Phosphatidylserine peroxidation during apoptosis. A signaling pathway for phagocyte clearance.
- Neurology of systemic autoimmune disorders: a pediatric perspective.
- Brain glutamine synthetase activity and hyperoxia in neonatal rats.
- Inactivation of mammalian brain glutamine synthetase by oxygen radicals.
- Mechanisms of synergistic toxicity of the radioprotective agent, WR2721, and 6-hydroxydopamine.
- Whimpers and bangs: of death and dying in the nervous system.
- A neurologist's approach to neuroblastoma.
- Effects of neocarzinostatin upon the development of tumors from murine neuroblastoma cells.
- The roles of mitotic arrest and protein synthesis in induction of apoptosis and differentiation in neuroblastoma cells in culture.
- Neuroblastoma: a neurochemical approach.
- Integrated case studies and medical decision making: a novel, computer-assisted bridge from the basic sciences to the clinics.
- Differential membrane antioxidant effects of immediate and long-term estradiol treatment of MCF-7 breast cancer cells.
- Signal transduction for clinicians: why should we care?
- Interrater concordance for faculty grading of student performances in a problem-based learning course.
- Phenoxyl radicals of etoposide (VP-16) can directly oxidize intracellular thiols: protective versus damaging effects of phenolic antioxidants.
- Interaction between 6-hydroxydopamine and transferrin: "Let my iron go".
- Exploiting oxidative stress and signaling in chemotherapy of resistant neoplasms.
- Oxidative signaling pathway for externalization of plasma membrane phosphatidylserine during apoptosis.
- Phospholipid signaling in apoptosis: peroxidation and externalization of phosphatidylserine.
- Apoptosis in development and disease of the nervous system: II. Apoptosis in childhood neurologic disease.
- Neuronal ''differentiation'' of murine neuroblastoma cells induced by neocarzinostatin: neural cell adhesion molecules.
- Prevention of neocarzinostatin-induced cell death and morphologic change in SK-N-SH human neuroblastoma cells by continuous exposure to nerve growth factor.
- G-protein expression during enediyne-induced neurite outgrowth in neuroblastoma.
- Direct evidence for antioxidant effect of Bcl-2 in PC12 rat pheochromocytoma cells.
- Potentiation of enediyne-induced apoptosis and differentiation by Bcl-2.
- Nerve growth factor (NGF)-mediated protection of neural crest cells from antimitotic agent-induced apoptosis: the role of the low-affinity NGF receptor.
- Early events in Bcl-2-enhanced apoptosis.
- DNA microarray profiling of developing PS1-deficient mouse brain reveals complex and coregulated expression changes.
- Cell line dependence of Bcl-2-induced alteration of glutathione handling.
- Implementation of a longitudinal mentored scholarly project: an approach at two medical schools.
- Selective oxidation and externalization of membrane phosphatidylserine: Bcl-2-induced potentiation of the final common pathway for apoptosis.
- Glutamate-induced cytotoxicity in PC12 pheochromocytoma cells: role of oxidation of phospholipids, glutathione and protein sulfhydryls revealed by bcl-2 transfection.
- Adjunctive treatment of murine neuroblastoma with 6-hydroxydopamine and Tempol.
- Apoptosis in the absence of caspase 3.
- Bcl-2 mediates induction of neural differentiation.
- Bcl-2-mediated potentiation of neocarzinostatin-induced apoptosis: requirement for caspase-3, sulfhydryl groups, and cleavable Bcl-2.
- Cholesterol biosynthesis and the pro-apoptotic effects of the p75 nerve growth factor receptor in PC12 pheochromocytoma cells.
- Prevention of catecholaminergic oxidative toxicity by 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl and its recycling complex with polynitroxylated albumin, TEMPOL/PNA.
- The intracellular domain of p75NTR as a determinant of cellular reducing potential and response to oxidant stress.
- The p75 neurotrophin receptor in human development and disease.
- Neuroprotective effects of TEMPOL in central and peripheral nervous system models of Parkinson''s disease.
- Oxidation and cytotoxicity of 6-OHDA are mediated by reactive intermediates of COX-2 overexpressed in PC12 cells.
- Bcl-2 overexpression disrupts the morphology of PC12 cells through reduced ERK activation.
- p75NTR-dependent modulation of cellular handling of reactive oxygen species.
- New approaches to pharmacotherapy of tumors of the nervous system during childhood and adolescence.
- Pharmacotherapy for adults with tumors of the central nervous system.
- In-tube transfection improves the efficiency of gene transfer in primary neuronal cultures.
Schools
Weill Cornell Medical College
Doctors Specialties
- Pediatric Neurology
- Pediatrics
Accepted Insurances
Awards
- Top MD
Education
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Harvard Medical School -
Boston Children's Hospital -
Weill Cornell Medical College of Cornell University
Hospital
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Strong Memorial Hospital of the University of Rochester
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