Director, Division of Pediatric Gastroenterology and Nutrition and Professor, Pediatrics Washington University, St. Louis
Pediatric Gastroenterology
Dr. Phillip I. Tarr, MD
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Doctor Phillip I. Tarr, MD works in the field of Pediatric Gastroenterology. He attended Yale University School of Medicine. Yale University School of Medicine is a top medical university. Yale University School of Medicine is ranked 7/57 in Research/PrimaryCare. He over the years received 1 awards: "Blackwell Scientific Research Scholar Award". Phillip I. Tarr is a published doctor and has 97 publications published. The lastest was: 'The immunohistological diagnosis of E. coli O157:H7 colitis: possible association with colonic ischemia.'
Publications
- Environmental Enteric Dysfunction Includes a Broad Spectrum of Inflammatory Responses and Epithelial Repair Processes.
- Shiga Toxin-Producing Escherichia coli Infection, Antibiotics, and Risk of Developing Hemolytic Uremic Syndrome: A Meta-Analysis.
- Environmental enteric dysfunction: pathogenesis, diagnosis, and clinical consequences.
- Use of the lactulose to mannitol ratio to evaluate childhood environmental enteric dysfunction: a systematic review.
- Shiga Toxin-Producing Escherichia coli: a Single-Center, 11-Year Pediatric Experience.
- Phenotypic and genotypic analysis of Clostridium difficile isolates: a single center study.
- Small Bowel Resection Induces Long-Term Changes in the Enteric Microbiota of Mice.
- Development of an enhanced human gastrointestinal epithelial culture system to facilitate patient-based assays.
- Sepsis From the Gut: The Enteric Habitat of Bacteria That Cause Late-Onset Neonatal Bloodstream Infections.
- Unexplained benefits of antibiotics in childhood: empiricism in need of enlightenment.
- Fecal Carriage of Methicillin Resistant Staphylococcus aureus (MRSA) and Vancomycin Resistant Enterococcus (VRE) in Healthy Children.
- Precise Dissection of an Escherichia coli O157:H7 outbreak by Single Nucleotide Polymorphism Analysis.
- Treatment of Shiga Toxin-Producing Escherichia coli Infections.
- Intestinal Inflammatory Biomarkers and Outcome in Pediatric Clostridium difficile Infections.
- Viral Co-infections are Common and are Associated with Higher Bacterial Burden in Children with C. difficile Infection.
- Validation of the Modified Vesikari Score in Children with GastroEnteritis in 5 U.S. Emergency Departments.
- Markers of Intestinal Inflammation, not Bacterial Burden, Correlate with Clinical Outcomes in Clostridium difficile Infection.
- Use and accuracy of diagnostic imaging by hospital type in pediatric appendicitis.
- The CXCR4/CXCR7/SDF-1 pathway contributes to the pathogenesis of Shiga toxin-associated hemolytic uremic syndrome in humans and mice.
- Early Volume Expansion During Diarrhea and Relative Nephroprotection During Subsequent Hemolytic Uremic Syndrome.
- Obscured Phylogeny and Recombinational Dormancy in Escherichia coli.
- Bacterial DNA content in the intestinal wall from infants with necrotizing enteroColitis.
- Proinflammatory fecal mRNA and childhood bacterial enteric infections.
- Shiga toxin 1 interaction with enterocytes causes apical protein mistargeting through the depletion of intracellular galectin-3.
- Deer sausage: a newly identified vehicle of transmission of Escherichia coli O157:H7.
- A precise reconstruction of the emergence and constrained radiations of Escherichia coli O157 portrayed by backbone concatenomic analysis.
- Acute bloody diarrhea: a medical emergency for patients of all ages.
- Parental management of childhood diarrhea.
- Tri-county comprehensive assessment of risk factors for sporadic reportable bacterial enteric infection in children.
- Shiga toxin-associated hemolytic uremic syndrome and thrombotic thrombocytopenic purpura: distinct mechanisms of pathogenesis.
- Detection and characterization of the fimbrial sfp cluster in enterohemorrhagic Escherichia coli O165:H25/NM isolates from humans and cattle.
- Enteric infections and diagnostic testing.
- Shiga-toxin producing Escherichia coli and the hemolytic uremic syndrome: what have we learned in the past 25 years?
- Prevalence and mechanisms of broad-spectrum beta-lactam resistance in Enterobacteriaceae: a children's hospital experience.
- Loop-mediated isothermal amplification assay for rapid detection of common strains of Escherichia coli.
- Isolation of patients acutely infected with Escherichia coli O157:H7: low-tech, highly effective prevention of hemolytic uremic syndrome.
- Metagenomic analysis of human diarrhea: viral detection and discovery.
- Shiga toxin gene loss and transfer in vitro and in vivo during enterohemorrhagic Escherichia coli O26 infection in humans.
- Greater diversity of Shiga toxin-encoding bacteriophage insertion sites among Escherichia coli O157:H7 isolates from cattle than in those from humans.
- Diarrhea etiology in a Children's Hospital Emergency Department: a prospective cohort study.
- Ciprofloxacin-resistant gram-negative bacilli in the fecal microflora of children.
- Proteomics-based expression library screening (PELS): a novel method for rapidly defining microbial immunoproteomes.
- Lipopolysaccharide from enterohemorrhagic Escherichia coli binds to platelets through TLR4 and CD62 and is detected on circulating platelets in patients with hemolytic...
- Expression of putative virulence factors of Escherichia coli O157:H7 differs in bovine and human infections.
- Molecular profiling and phenotype analysis of Escherichia coli O26:H11 and O26:NM: secular and geographic consistency of enterohemorrhagic and enteropathogenic isolates.
- Relative nephroprotection during Escherichia coli O157:H7 infections: association with intravenous volume expansion.
- Use of in vivo-induced antigen technology for identification of Escherichia coli O157:H7 proteins expressed during human infection.
- The IrgA homologue adhesin Iha is an Escherichia coli virulence factor in murine urinary tract infection.
- Etiology of diarrhea in pediatric outpatient settings.
- Phenotypic and molecular analysis of tellurite resistance among enterohemorrhagic Escherichia coli O157:H7 and sorbitol-fermenting O157:NM clinical isolates.
- Confirmation of an old adage: you find what you seek.
- Shiga toxin antigen detection should not replace sorbitol MacConkey agar screening of stool specimens.
- High-frequency secondary mutations after suicide-driven allelic exchange mutagenesis in extraintestinal pathogenic Escherichia coli.
- Shiga toxin-producing Escherichia coli in Montana: bacterial genotypes and clinical profiles.
- Escherichia coli O157:H7 Shiga toxin-encoding bacteriophages: integrations, excisions, truncations, and evolutionary implications.
- Hemolytic uremic syndrome in association with typhoid fever.
- Single multiplex polymerase chain reaction to detect diverse loci associated with diarrheagenic Escherichia coli.
- Risk of hemolytic uremic syndrome from antibiotic treatment of Escherichia coli O157:H7 Colitis.
- Molecular characterization of a serotype O121:H19 clone, a distinct Shiga toxin-producing clone of pathogenic Escherichia coli.
- Shiga toxin-producing Escherichia coli in children with diarrhea: a prospective point-of-care study.
- Escherichia coli O157:H7 infections: discordance between filterable fecal shiga toxin and Disease outcome.
- Analysis of urinary Escherichia coli isolates for ability to produce Shiga toxin.
- Basic fibroblast growth factor and Shiga toxin-O157:H7-associated hemolytic uremic syndrome.
- ABO and P1 blood group antigen expression and stx genotype and outcome of childhood Escherichia coli O157:H7 infections.
- Prothrombotic coagulation abnormalities preceding the hemolytic-uremic syndrome.
- Pediatric fecal microbiota harbor diverse and novel antibiotic resistance genes.
- Cooperative assembly of androgen receptor into a nucleoprotein complex that regulates the prostate-specific antigen enhancer.
- Molecular cloning of Schistosoma mansoni myosin.
- LR1: a candidate RNA virus of Leishmania.
- Immunisation with a polyvalent pneumococcal vaccine. Reduction of adult respiratory mortality in a New Guinea Highlands community.
- Primary meningococcal pericarditis. Diagnosis by counter-current immunoelectrophoresis.
- Acute gastric dilatation in Duchenne muscular dystrophy: a case report and review of the literature.
- Comparison of methods for the isolation of genital mycoplasmas from men.
- Demographic factors in the epidemiology of hemophilus influenzae meningitis in young children.
- Hyperbilirubinemia secondary to delayed absorption of intraperitoneal blood following intrauterine transfusion.
- Bacterial DNA in mixed cholesterol gallstones.
- "4+ normal flora" (or is it?)
- Food-borne and water-borne infections and the gastroenterologist.
- The immunohistological diagnosis of E. coli O157:H7 Colitis: possible association with colonic ischemia.
- The ecology and pathobiology of Clostridium difficile infections: an interdisciplinary challenge.
- Antimotility agents and E. coli infection.
- Activation of endothelial-leukocyte adhesion molecule 1 (ELAM-1) gene transcription.
- EnteroColitis associated with Shiga-like toxin production: an appropriate animal model at last?
- Etiology and outcome of diarrhea after marrow transplantation: a prospective study.
- Hemolytic uremic syndrome epidemiology: a population-based study in King County, Washington, 1971 to 1980.
- A PCR specific for Escherichia coli O157 based on the rfb locus encoding O157 lipopolysaccharide.
- Escherichia coli O157:H7 in retail ground beef in Seattle: results of a one-year prospective study.
- The prevalence of Escherichia coli O157.H7 in dairy and beef cattle in Washington State.
- Antibiotic resistance and O antigen expression in Escherichia coli.
- von Willebrand factor and von Willebrand factor-cleaving metalloprotease activity in Escherichia coli O157:H7-associated hemolytic uremic syndrome.
- Recent advances and evidence gaps in persistent diarrhea.
- Lessons learned in the management of hemolytic uremic syndrome in children.
- Evaluation of DNA probes for detection of Shiga-like-toxin-producing Escherichia coli in food and calf fecal samples.
- Molecular epidemiology of Escherichia coli O157:H7 strains by bacteriophage lambda restriction fragment length polymorphism analysis: application to a multistate foodb...
- A longitudinal study of Escherichia coli O157 in fourteen cattle herds.
- Associations between bovine, human, and raw milk, and beef isolates of non-O157 Shiga toxigenic Escherichia coli within a restricted geographic area of the United States.
Schools
Yale University
University Wash Chldns or Hospital
University of Washington
Procedures Preformed
- Colonoscopy, Proctosigmoidoscopy, and Sigmoidoscopy
Conditions Treated
- Crohn's Disease (Regional Enteritis)
- Esophageal Varices
- Gastroesophageal Reflux Disease (GERD)
- Ulcerative Colitis
Doctors Specialties
- Pediatric Gastroenterology
Accepted Insurances
- Aetna HMO
- Choice Plus POS II
- Anthem Blue Cross Blue Shield PPO
- Blue Card PPO
- Blue Cross Blue Shield of Illinois PPO
- Cigna HMO
- Cigna PPO
- Great West Healthcare-Cigna PPO
- LocalPlus
- Open Access Plus
- Commercial Insurance Company
- Coventry Health Care of Illinois PPO
- Health and Life PPO
- Coventry Health Care of Missouri PPO
- Golden Rule
- HealthLink PPO
- Homestate Health Plan
- Choice Care PPO
- Medicaid
- Medicare MCR
- MultiPlan PPO
- PHCS Network PPO
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
- United Healthcare
Awards
- Blackwell Scientific Research Scholar Award
Education
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University of Washington -
Yale University School of Medicine
Hospital
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St. Louis Children's Hospital -
Barnes-Jewish Hospital
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