Professor, Psychiatry, Yale University School of Medicine
Psychiatry
Dr. Robert T. Malison, MD
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Robert Malison works in the field of Psychiatry. He studied medicine at Yale University School of Medicine. Yale University School of Medicine is a top medical university. Yale University School of Medicine has a rank of 7 in research and a 57 in primary care He has 1 awards "Top Doctors: New York Metro Area". Robert Malison is a published doctor and has 101 publications published. The lastest was: 'Reduced brain serotonin transporter availability in major depression as measured by [123I]-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane and single photon emission ...'
Publications
- Modafinil and sleep architecture in an inpatient-outpatient treatment study of cocaine dependence.
- Age-related changes in binding of the D2/3 receptor radioligand [(11)C](+)PHNO in healthy volunteers.
- Deficits in Prefrontal Cortical and Extrastriatal Dopamine Release in Schizophrenia: A Positron Emission Tomographic Functional Magnetic Resonance Imaging Study.
- Ancestry informative markers for distinguishing between Thai populations based on genome-wide association datasets.
- Altered neural correlates of reward and loss processing during simulated slot-machine fMRI in pathological gambling and cocaine dependence.
- An exploratory examination of marijuana use, problem-gambling severity, and health correlates among adolescents.
- The effects of methylphenidate on resting-state striatal, thalamic and global functional connectivity in healthy adults.
- Parametric Imaging and Test-Retest Variability of 11C-(+)-PHNO Binding to D2/D3 Dopamine Receptors in Humans on the High-Resolution Research Tomograph PET Scanner.
- Dopamine D3 receptor alterations in cocaine-dependent humans imaged with [(11)C](+)PHNO.
- Methylphenidate remediates error-preceding activation of the default mode brain regions in cocaine-addicted individuals.
- Rare ADH Variant Constellations are Specific for Alcohol Dependence.
- A single-day paradigm of self-regulated human cocaine administration.
- Age Effects on Serotonin Receptor 1B as Assessed by PET.
- Genome-Wide Association Study of Alcohol Dependence Implicates KIAA0040 on Chromosome 1q.
- Clinically relevant doses of methylphenidate significantly occupy norepinephrine transporters in humans in vivo.
- Biological markers of the effects of intravenous methylphenidate on improving inhibitory control in cocaine-dependent patients.
- Regulation of cocaine self-administration in humans: lack of evidence for loading and maintenance phases.
- Normalizing effects of modafinil on sleep in chronic cocaine users.
- PET imaging of the effects of age and cocaine on the norepinephrine transporter in the human brain using (S,S)-[(11)C]O-methylreboxetine and HRRT.
- Sex differences in sleep and sleep-dependent Learning in abstinent cocaine users.
- Chest tightness and palpitations associated with modafinil and consumption of free glutamate.
- Cocaine users differ from normals on cognitive tasks which show poorer performance during drug abstinence.
- Pilot study of lorazepam and tiagabine effects on sleep, motor Learning, and impulsivity in cocaine abstinence.
- Dopamine beta-hydroxylase gene (DbetaH) -1021C-->T influences self-reported paranoia during cocaine self-administration.
- Beneficial effects of the glutamate-modulating agent riluzole on disordered eating and pathological skin-picking behaviors.
- Self-reported paranoia during laboratory "binge" cocaine self-administration in humans.
- Sex differences in diencephalon serotonin transporter availability in major depression.
- Riluzole augmentation in treatment-resistant obsessive-compulsive disorder: an open-label trial.
- Increased dopamine transporter availability associated with the 9-repeat allele of the SLC6A3 gene.
- Brain serotonin transporter availability predicts treatment response to selective serotonin reuptake inhibitors.
- Cerebrospinal fluid corticotropin-releasing factor and perceived early-life stress in depressed patients and healthy control subjects.
- Central serotonin transporter availability measured with [123I]beta-CIT SPECT in relation to serotonin transporter genotype.
- Changes in human in vivo serotonin and dopamine transporter availabilities during chronic antidepressant administration.
- Genotype-controlled analysis of plasma dopamine beta-hydroxylase activity in psychotic unipolar major depression.
- Unaltered dopamine transporter availability in adult attention deficit hyperactivity disorder.
- Age-related decline in dopamine transporters: analysis of striatal subregions, nonlinear effects, and hemispheric asymmetries.
- Cerebrospinal fluid interleukin (IL)-6 in unipolar major depression.
- A paradigm to investigate the self-regulation of cocaine administration in humans.
- Sleep architecture, cocaine and visual Learning.
- Retrograde effects of triazolam and zolpidem on sleep-dependent motor Learning in humans.
- Subjective responses and cardiovascular effects of self-administered cocaine in cocaine-abusing men and women.
- Cocaine and sleep: early abstinence.
- Risk factors for cocaine-induced paranoia in cocaine-dependent sibling pairs.
- N-acetylcysteine augmentation in serotonin reuptake inhibitor refractory obsessive-compulsive disorder.
- Sleep, sleep-dependent procedural Learning and vigilance in chronic cocaine users: Evidence for occult insomnia.
- Striatal dopamine transporter availability with [123I]beta-CIT SPECT is unrelated to gender or menstrual cycle.
- Demographic changes and marker properties affect detection of human population differentiation.
- Human clock, PER1 and PER2 polymorphisms: lack of association with cocaine dependence susceptibility and cocaine-induced paranoia.
- Identification of population substructure among Jews using STR markers and dependence on reference populations included.
- Increased error-related thalamic activity during early compared to late cocaine abstinence.
- Adolescent cannabis use increases risk for cocaine-induced paranoia.
- Inter-rater reliability and concurrent validity of DSM-IV opioid dependence in a Hmong isolate using the Thai version of the Semi-Structured Assessment for Drug Depend...
- A multistudy analysis of the effects of early cocaine abstinence on sleep.
- Southeast Asian origins of five Hill Tribe populations and correlation of genetic to linguistic relationships inferred with genome-wide SNP data.
- A paradigm to investigate the regulation of cocaine self-administration in human cocaine users: a randomized trial.
- A quantitative-trait analysis of human plasma-dopamine beta-hydroxylase activity: evidence for a major functional polymorphism at the DBH locus.
- Age-related decline in central serotonin transporter availability with [(123)I]beta-CIT SPECT.
- Genetic polymorphism at the CLOCK gene locus and major depression.
- Elevated central serotonin transporter binding availability in acutely abstinent cocaine-dependent patients.
- A haplotype at the DBH locus, associated with low plasma dopamine beta-hydroxylase activity, also associates with cocaine-induced paranoia.
- Limited efficacy of ketoconazole in treatment-refractory major depression.
- Reduced brain serotonin transporter availability in major depression as measured by [123I]-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane and single photon emission ...
- Lithium and desipramine versus desipramine alone in the treatment of severe major depression: a preliminary study.
- Imaging of the serotonergic system: interactions of neuroanatomical and functional abnormalities of depression.
- RE: Logan et al., 1997.
- [123I]beta-CIT SPECT imaging of dopamine transporter availability after mazindol administration in human cocaine addicts.
- Dopamine beta-hydroxylase: two polymorphisms in linkage disequilibrium at the structural gene DBH associate with biochemical phenotypic variation.
- Elevated striatal dopamine transporters during acute cocaine abstinence as measured by [123I] beta-CIT SPECT.
- The neurobiology of tryptophan depletion in depression: effects of intravenous tryptophan infusion.
- Plasma homovanillic acid and the dopamine transporter during cocaine withdrawal.
- Effects of acute tryptophan depletion in lithium-remitted manic patients: a pilot study.
- Neurobiology of tryptophan depletion in depression: effects of m-chlorophenylpiperazine (mCPP).
- Ciliary neurotrophic factor null allele frequencies in schizophrenia, affective Disorders, and Alzheimer's disease.
- Effects of antiglucocorticoid treatment on 5-HT1A function in depressed patients and healthy subjects.
- Pharmacokinetics of the three radioiodinated dopamine D2 receptor ligands [123I]IBF, [123I]epidepride and [123I]2''-ISP in nonhuman primates.
- Comparison of three high affinity SPECT radiotracers for the dopamine D2 receptor.
- Positron emission tomography measurement of cerebral metabolic correlates of tryptophan depletion-induced depressive relapse.
- Efficacy of papaverine addition for treatment-refractory major depression.
- Microdialysis and SPECT measurements of amphetamine-induced dopamine release in nonhuman primates.
- Seasonal variation in neuroendocrine and mood responses to i.v. L-tryptophan in depressed patients and healthy subjects.
- Neuropsychological abnormalities in cocaine abusers: possible correlates in SPECT neuroimaging.
- Euphorigenic doses of cocaine reduce [123I]beta-CIT SPECT measures of dopamine transporter availability in human cocaine addicts.
- Yohimbine augmentation of fluvoxamine in refractory depression: a single-blind study.
- Striatal dopamine transporter imaging in nonhuman primates with iodine-123-IPT SPECT.
- [123I]iomazenil SPECT imaging demonstrates significant benzodiazepine receptor reserve in human and nonhuman primate brain.
- Evaluation of the monoamine uptake site ligand [123I]methyl 3 beta-(4-iodophenyl)-tropane-2 beta-carboxylate ([123I]beta-CIT) in non-human primates: pharmacokinetics, ...
- Computer-assisted coregistration of multislice SPECT and MR brain images by fixed external fiducials.
- Noradrenergic dysregulation during discontinuation of cocaine use in addicts.
- In vitro and in vivo characterization of R(+)-FIDA2: a dopamine D2-like imaging agent.
- Age-related decline in striatal dopamine transporter binding with iodine-123-beta-CITSPECT.
- Antiglucocorticoid treatment of refractory depression with ketoconazole: a case report.
- SPECT imaging of dopamine and serotonin transporters with [123I]beta-CIT: pharmacological characterization of brain uptake in nonhuman primates.
- [123I]beta-CIT SPECT imaging of striatal dopamine transporter binding in Tourette's disorder.
- Development of a system to simplify identification of peptides and their catabolites in a high-performance liquid chromatographic effluent.
- Phosphorylation of the GABAa/benzodiazepine receptor alpha subunit by a receptor-associated protein kinase.
- [123I]-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane: high-affinity SPECT radiotracer of monoamine reuptake sites in brain.
- SPECT imaging of the benzodiazepine receptor: feasibility of in vivo potency measurements from stepwise displacement curves.
- SPECT imaging of the benzodiazepine receptor in non-human primate brain with [123I]Ro 16-0154.
- Amphetamine-stimulated dopamine release competes in vivo for [123I]IBZM binding to the D2 receptor in nonhuman primates.
- Pharmacokinetics of the SPECT benzodiazepine receptor radioligand [123I]iomazenil in human and non-human primates.
Schools
Yale University
Hospital Of St Raphael
Conditions Treated
- Developmental and Learning Disorders
- Schizophrenia
Doctors Specialties
- Addiction Psychiatry
- Psychiatry
Accepted Insurances
Awards
- Top Doctors: New York Metro Area
Education
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Yale New Haven Children's Center -
Yale University School of Medicine
Hospital
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Yale-New Haven Hospital
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