Director, The Univ. of Kansas Cancer Center
Pathology
Dr. Roy A. Jensen, MD
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Jensen practices Pathology. He went to medical school at Vanderbilt University School of Medicine. Jensen has written publications. He has 45 publications published with PubMed. The lastest publication is: 'A phase I trial of retroviral BRCA1sv gene therapy in ovarian cancer.'
Publications
- Heat Shock Factor 1 in Protein Homeostasis and Oncogenic Signal Integration.
- Honokiol inhibits melanoma stem cells by targeting notch signaling.
- BRCA1 regulation of epidermal growth factor receptor (EGFR) expression in human breast cancer cells involves microRNA-146a and is critical for its tumor suppressor fun...
- Honokiol affects melanoma cell growth by targeting the AMP-activated protein kinase signaling pathway.
- PKCλ/ι signaling promotes triple-negative breast cancer growth and metastasis.
- Germline BRCA mutation evaluation in a prospective triple-negative breast cancer registry: implications for hereditary breast and/or ovarian cancer syndrome testing.
- The prognostic value of BRCA1 promoter methylation in early stage triple negative breast cancer.
- Prolactin induces Notch signaling in a Jak2-STAT and Jak2-ERK pathways in colon cancer stem and progenitor cells.
- Evidence of functional cross-talk between the Notch and NF-κB pathways in non-neoplastic hyperproliferating colonic epithelium.
- BRCA1 and HSP90 cooperate in homologous and non-homologous DNA double-strand-break repair and G2/M checkpoint activation.
- Identifying and exploiting defects in the Fanconi anemia/BRCA pathway in oncology.
- Genetic and epigenetic signatures of breast cancer subtypes.
- 3,5-bis (2,4-difluorobenzylidene)-4-piperidone, a novel compound that affects pancreatic cancer growth and angiogenesis.
- A specialized aspartokinase enhances the biosynthesis of the osmoprotectants ectoine and hydroxyectoine in Pseudomonas stutzeri A1501.
- RNA binding protein CUGBP2/CELF2 mediates curcumin-induced mitotic catastrophe of pancreatic cancer cells.
- Cohesion group approach for evolutionary analysis of aspartokinase, an enzyme that feeds a branched network of many biochemical pathways.
- A human breast cell model of preinvasive to invasive transition.
- Cohesion group approach for evolutionary analysis of TyrA, a protein family with wide-ranging substrate specificities.
- Excellent survival, cancer type, and Nottingham grade after atypical lobular hyperplasia on initial breast biopsy.
- Lobulocentricity of breast hypersecretory hyperplasia with cytologic atypia: infrequent association with carcinoma in situ.
- Proteomics in diagnostic pathology: profiling and imaging proteins directly in tissue sections.
- Transgenic mice expressing a dominant-negative mutant type II transforming growth factor-beta receptor exhibit impaired mammary development and enhanced mammary tumor ...
- Ancient origin of the tryptophan operon and the dynamics of evolutionary change.
- Metaplastic spindle cell breast tumors arising within papillomas, complex sclerosing lesions, and nipple adenomas.
- Ductal carcinoma in situ of the breast: impact of pathology on therapeutic decisions.
- Direct analysis of laser capture microdissected cells by MALDI mass spectrometry.
- The correct phylogenetic relationship of KdsA (3-deoxy-d-manno-octulosonate 8-phosphate synthase) with one of two independently evolved classes of AroA (3-deoxy-d-arab...
- Chlamydia exploit the mammalian tryptophan-depletion defense strategy as a counter-defensive cue to trigger a survival state of persistence.
- The subsystems approach to genome annotation and its use in the project to annotate 1000 genomes.
- An adenoviral vector containing an arg-gly-asp (RGD) motif in the fiber knob enhances protein product levels from transgenes refractory to expression.
- Effects of BRCA1 transgene expression on murine mammary gland development and mutagen-induced mammary neoplasia.
- Evolution of bacterial trp operons and their regulation.
- Dynamic diversity of the tryptophan pathway in chlamydiae: reductive evolution and a novel operon for tryptophan recapture.
- Lateral gene transfer and ancient paralogy of operons containing redundant copies of tryptophan-pathway genes in Xylella species and in heterocystous cyanobacteria.
- Atypical lobular hyperplasia as a unilateral predictor of breast cancer risk: a retrospective cohort study.
- Significance of two distinct types of tryptophan synthase beta chain in Bacteria, Archaea and higher plants.
- The TyrA family of aromatic-pathway dehydrogenases in phylogenetic context.
- Inter-genomic displacement via lateral gene transfer of bacterial trp operons in an overall context of vertical genealogy.
- A core catalytic domain of the TyrA protein family: arogenate dehydrogenase from Synechocystis.
- A training-testing approach to the molecular classification of resected non-small cell lung cancer.
- A phase I trial of retroviral BRCA1sv gene therapy in ovarian cancer.
- Ovarian cancer gene therapy.
- Continued local recurrence of carcinoma 15-25 years after a diagnosis of low grade ductal carcinoma in situ of the breast treated only by biopsy.
- Diagnostic criteria and cancer risk of proliferative breast lesions.
Schools
Vanderbilt University
Vanderbilt
Nci
Doctors Specialties
- Anatomic Pathology
- Pathology
Accepted Insurances
Education
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National Institutes of Health Clinical Center -
Vanderbilt University -
Vanderbilt University School of Medicine
Hospital
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The University of Kansas Hospital
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