Physician
Pathology
Dr. Serhan Alkan, MD
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Dr. Serhan Alkan practices Pathology. Serhan Alkan is a published doctor. He has 51 papers published. The most current publication "Glucocorticoids inhibit human antigen-specific and enhance total IgE and IgG4 production due to differential effects on T and B cells in vitro." He accepts all Medicare patients.
Publications
- The transcription factors Ik-1 and MZF1 downregulate IGF-IR expression in NPM-ALK(+) T-cell Lymphoma.
- Myeloid expression of angiotensin-converting enzyme facilitates Myeloid maturation and inhibits the development of Myeloid-derived suppressor cells.
- Crizotinib (PF-2341066) induces apoptosis due to downregulation of pSTAT3 and BCL-2 family proteins in NPM-ALK(+) anaplastic large cell Lymphoma.
- Chronic Myelomonocytic Leukemia Monocytes Uniformly Display a Population of Monocytes With CD11c Underexpression.
- Bruton tyrosine kinase is commonly overexpressed in mantle cell Lymphoma and its attenuation by Ibrutinib induces apoptosis.
- Immunohistochemical localization of phosphorylated AKT in multiple Myeloma.
- Analysis of c-kit protein expression in small-cell lung carcinoma and its implication for prognosis.
- Hairy cell Leukemia variant developing in a background of polycythemia vera.
- Rapid polymerase chain reaction-based confirmation of cat scratch Disease and Bartonella henselae infection.
- Protein kinase C-delta is commonly expressed in multiple Myeloma cells and its downregulation by rottlerin causes apoptosis.
- Analysis of signal transducer and activator of transcription 3 (STAT3) in gastrointestinal stromal tumors.
- Comparative studies of resistin expression and phylogenomics in human and mouse.
- IL-4 induces differentiation and expansion of Th2 cytokine-producing eosinophils.
- Fatal hemorrhagic pneumonia concomitant with Chlamydia pneumoniae and parainfluenza virus 4 infection.
- Treatment of human chronic lymphocytic Leukemia cells with the proteasome inhibitor bortezomib promotes apoptosis.
- Hemophagocytic lymphohistiocytosis presenting with nonImmune hydrops fetalis.
- Overexpression of the NOTCH ligand JAG2 in malignant plasma cells from multiple Myeloma patients and cell lines.
- Cutting edge: IL-5 primes Th2 cytokine-producing capacity in eosinophils through a STAT5-dependent mechanism.
- Survival role of protein kinase C (PKC) in chronic lymphocytic Leukemia and determination of isoform expression pattern and genes altered by PKC inhibition.
- A unique case of Acute promyelocytic leukemia showing monocytic differentiation after ATRA (all-trans retinoic acid) therapy.
- Induction of apoptosis and down regulation of cell cycle proteins in mantle cell Lymphoma by flavopiridol treatment.
- p38gamma mitogen-activated protein kinase integrates signaling crosstalk between Ras and estrogen receptor to increase breast cancer invasion.
- Bromodomain and histone acetyltransferase domain specificities control mixed lineage Leukemia phenotype.
- Osseous metaplasia in diffuse large B-cell Lymphoma of the kidney.
- Immunostaining for SYT protein discriminates synovial sarcoma from other soft tissue tumors: analysis of 146 cases.
- Nodal ALK positive anaplastic large cell Lymphoma of the axilla with spontaneous regression.
- HSP90 inhibitor 17AAG causes apoptosis in ATRA-resistant Acute promyelocytic leukemia cells.
- Bortezomib induces apoptosis in T-cell prolymphocytic Leukemia (T-PLL).
- t(8;13)-positive bilineal Lymphomas: report of 6 cases.
- Histone deacetylase inhibitor romidepsin has differential activity in core binding factor Acute myeloid leukemia.
- Hydroxyurea, azacitidine and gemtuzumab ozogamicin therapy in patients with previously untreated non-M3 Acute myeloid leukemia and high-risk myelodysplastic syndromes ...
- c-Myc-mediated control of cell fate in megakaryocyte-erythrocyte progenitors.
- Precursor B-cell Acute lymphoblastic leukaemia with FAB L3 (i.e., Burkitt''s leukaemia/lymphoma) morphology and co-expression of monoclonal surface light chains and Td...
- Mice lacking the IFN-gamma receptor have impaired ability to resolve a lung eosinophilic inflammatory response associated with a prolonged capacity of T cells to exhib...
- Characterization of accessory cells required for helper T cell induction in vitro: evidence for a phagocytic, Fc-receptor, and Ia-bearing cell type.
- Effects of a new protein kinase C inhibitor CGP 41251 on T cell functions: inhibition of activation, growth, and target cell killing.
- A sensitive peptide mapping method. Identification of three amino acid substitutions within two anti-azobenzenearsonate monoclonal antibody light chains.
- Thrombin specificity. Selective cleavage of antibody light chains at the joints of variable with joining regions and joining with constant regions.
- Direct measurement of cytokines (IFN-gamma, IL-4, -5, and -6) from organs after antigenic challenge.
- The complete amino acid sequence of the light chain variable region of two monoclonal anti-p-azobenzene-arsonate antibodies bearing the cross-reactive idiotype.
- Induction and differential regulation of bee venom phospholipase A2-specific human IgE and IgG4 antibodies in vitro requires allergen-specific and nonspecific activati...
- Prostaglandin E2 (PGE2)-dependent suppression of interleukin alpha (IL-2) production in patients with major trauma.
- The cross-reactive idiotype of anti-4-azobenzenearsonate hybridoma-derived antibodies in A/J mice constitutes multiple heavy chains.
- Structural and serological analysis of cross-reactive idiotypes: comparison of heavy and light chain families of anti-arsonate antibodies.
- Glucocorticoids inhibit human antigen-specific and enhance total IgE and IgG4 production due to differential effects on T and B cells in vitro.
- Epitope-specific T cell tolerance to phospholipase A2 in bee venom immunotherapy and recovery by IL-2 and IL-15 in vitro.
- Tenascin, an extracellular matrix protein, exerts immunomodulatory activities.
- Structural characterization of antiidiotypic antibodies. Evidence that Ab2s are derived from the germline differently than Ab1s.
- Antigen-induced proliferation assay for mouse T lymphocytes. Response to a monovalent antigen.
- A Case of Cutaneous Plasmablastic Lymphoma in HIV/AIDS with Disseminated Cryptococcus.
Schools
Ege University Medical Faculty
George Washington University
University Of Michigan
Conditions Treated
- Acute Leukemia
- Anemia
- Antiphospholipid Syndrome (APS)
- Chronic Myeloid Leukemia (CML)
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Doctors Specialties
- Hematology
- Hematopathology
- Pathology
Accepted Insurances
- Aetna
- Blue Card PPO
- Advantage Preferred DirectAccess Plus PPO
- Blue Cross Blue Shield of California PPO
- Pathway X Direct Access PPO
- Pathway X Tiered Direct Access
- Select PPO
- Commercial Insurance Company
- Coventry Health Care
- Delta Health System
- Medicaid
- Medicare MCR
- Heritage Signature
Education
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University of Michigan Hospitals and Health Centers -
George Washington University -
Ege University Faculty of Medicine
Hospital
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Cedars-Sinai Medical Center
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1407835507 |
| Last Name Of The Provider | ALKAN |
| First Name Of The Provider | SERHAN |
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