Physician

Pathology

Vincent T. Marchesi works in the field of Pathology. He graduated from Yale University School of Medicine. Yale University School of Medicine is a top medical college. Yale University School of Medicine is ranked 7 in research and 57 in primary care medicine He received awards:"Elected Member". Vincent T. Marchesi is a published doctor as well. He has 93 publications published. The latest was: From molecular analysis to medical practice: recent studies reveal new therapeutic targets for an old medicine.

Publications

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• Gain-of-function somatic mutations contribute to inflammation and blood vessel damage that lead to Alzheimer dementia: a hypothesis.
• Alzheimer's disease and CADASIL are heritable, adult-onset dementias that both involve damaged small blood vessels.
• Alzheimer's disease 2012: the great amyloid gamble.
• Alzheimer's dementia begins as a disease of small blood vessels, damaged by oxidative-induced inflammation and dysregulated amyloid metabolism: implications for early ...
• Requirement for AHNAK1-mediated calcium signaling during T lymphocyte cytolysis.
• The relevance of research on red cell membranes to the understanding of complex human disease: a personal perspective.
• A scaffold protein, AHNAK1, is required for calcium signaling during T cell activation.
• An alternative interpretation of the amyloid Abeta hypothesis with regard to the pathogenesis of Alzheimer's disease.
• The AHNAKs are a class of giant propeller-like proteins that associate with calcium channel proteins of cardiomyocytes and other cells.
• Selective solubilization of a protein component of the red cell membrane.
• Mechanisms of cell migration and macromolecule transport across the walls of blood vessels.
• Protein 4.1 is involved in a structural thermotropic transition of the red blood cell membrane detected by a spin-labeled stearic acid.
• 31P nuclear magnetic resonance evidence for polyphosphoinositide associated with the hydrophobic segment of glycophorin A.
• Molecular features of integral membrane proteins of the human red cell membrane.
• Fractionation of the major sialoglycopeptides of the human red blood cell membrane.
• The binding of vimentin to human erythrocyte membranes: a model system for the study of intermediate filament-membrane interactions.
• Cloning of a portion of the chromosomal gene for human erythrocyte alpha-spectrin by using a synthetic gene fragment.
• Inactivation of adenosine triphosphatase and disruption of red cell membrances by trypsin: protective effect of adenosine triphosphate.
• Amino-acid sequence and oligosaccharide attachment sites of human erythrocyte glycophorin.
• Identification of functional domains of human erythrocyte spectrin.
• Erythrocyte membrane protein band 3: its biosynthesis and incorporation into membranes.
• Biosynthesis of erythrocyte membrane protein band 3 in DMSO-induced Friend erythroleukemia cells.
• Functional components of surface membranes: potential targets for pharmacological manipulation.
• Isolation and characterization of peptides derived from the cytoplasmic segment of band 3, the predominant intrinsic membrane protein of the human erythrocyte.
• Proteolytic degradation of human erythrocyte band 3 by membrane-associated protease activity.
• Spectrin domains: proteolytic susceptibility as a probe of protein structure.
• The structural basis of ankyrin function. II. Identification of two functional domains.
• Spectrin oligomers: a structural feature of the erythrocyte cytoskeleton.
• Hollow cylinder protein in the cytoplasm of human erythrocytes.
• THE LOCALIZATION OF NUCLEOSIDEPHOSPHATASE ACTIVITY IN DIFFERENT TYPES OF SMALL BLOOD VESSELS.
• The role of pinocytic vesicles in the transport of materials across the walls of small blood vessels.
• Demonstration of the outer surface of freeze-etched red blood cell membranes.
• Studies on the major sialoglycoprotein of the human red cell membrane. Isolation and characterization of tryptic glycopeptides.
• Physical and chemical properties of a protein isolated from red cell membranes.
• A comparative study of spectrin: a protein isolated from red blood cell membranes.
• Some molecular features of integral membrane proteins.
• The cytoskeletal system of red blood cells.
• Orientation of glycoproteins in cell membranes.
• The red cell membrane.
• The red cell membrane skeleton: recent progress.
• The carboxyl-terminal domain of human erythrocyte band 3. Description, isolation, and location in the bilayer.
• Genomic structure of the locus encoding protein 4.1. Structural basis for complex combinational patterns of tissue-specific alternative RNA splicing.
• The localization of Mg-Na-K-activated adenosine triphosphatase on red cell ghost membranes.
• Functional adaptations of transbilayer proteins.
• A nonerythroid isoform of protein 4.1R interacts with the nuclear mitotic apparatus (NuMA) protein.
• From molecular analysis to medical practice: recent studies reveal new therapeutic targets for an old medicine.
• Hard days...on the endless frontier?...or in the trenches?
• The life sciences forum--a call for contributions.
• The localization of spectrin on the inner surface of human red blood cell membranes by ferritin-conjugated antibodies.
• The membrane skeleton as a potential target for toxic agents.
• Molecular cloning of the cDNA for human erythrocyte beta-spectrin.
• Molecular genetics of the human beta-spectrin gene.
• [Propositions for the selection and the delineation of peritumoral microscopic disease volumes in oral cavity and oropharyngeal cancers (lymph nodes excluded)].
• Erythrocyte membrane skeleton phosphoproteins: identification of two unrelated phosphoproteins in band 4.9.
• Asynchronous regulation of splicing events within protein 4.1 pre-mRNA during erythroid differentiation.
• The complete cDNA and polypeptide sequences of human erythroid alpha-spectrin.
• Sequence and exon-intron organization of the DNA encoding the alpha I domain of human spectrin. Application to the study of mutations causing hereditary elliptocytosis.
• Tissue-specific analogues of erythrocyte protein 4.1 retain functional domains.
• [Practical recommendations for breathing-adapted radiotherapy].
• [Extracranial stereotactic radiotherapy avancer by robotic radiosurgery: preliminary experience of the center Alexis-Vautrin].
• [Safety and quality assurance management in radiation oncology "what is the role for qualiticians?": example of the Centre Alexis Vautrin].
• [Comparative dosimetry study of two methods of intensity modulation performed on the same accelerator].
• Comparison of nonerythroid alpha-spectrin genes reveals strict homology among diverse species.
• Expression of specific isoforms of protein 4.1 in erythroid and non-erythroid tissues.
• Spectrin involvement in a 40 degrees C structural transition of the red blood cell membrane.
• Identification of proteolytically resistant domains of human erythrocyte spectrin.
• Evidence that spectrin binds to macromolecular complexes on the inner surface of the red cell membrane.
• Chemical characterization and surface orientation of the major glycoprotein of the human erythrocyte membrane.
• Spectrin: present status of a putative cyto-skeletal protein of the red cell membrane.
• Functional proteins of the human red blood cell membrane.
• Molecular analysis of insertion/deletion mutations in protein 4.1 in elliptocytosis. I. Biochemical identification of rearrangements in the spectrin/actin binding doma...
• Heterogeneity of mRNA and protein products arising from the protein 4.1 gene in erythroid and nonerythroid tissues.
• [High fetal irradiation: about one pregnant woman receiving infradiaphragmatic radiotherapy for Hodgkin lymphoma].
• [Long-term results and prognostic factors of squamous cell carcinoma of the anal canal treated by irradiation].
• In vitro assembly of multiprotein complexes containing alpha, beta, and gamma tubulin, heat shock protein HSP70, and elongation factor 1 alpha.
• Selective expression of an erythroid-specific isoform of protein 4.1.
• [Securitization of the bi-site radiotherapy activity as part of the resumption of treatments in the Hospital of Epinal by the team of Alexis Vautrin Nancy Cancer Center].
• Synthetic peptides mimic the assembly of transmembrane glycoproteins.
• [Optimisation and evaluation of the foetal dose during a radiotherapy of the right parotid].
• [Intensity-modulated radiation therapy for anal carcinoma].
• [CyberKnife robotic stereotactic radiotherapy: technical aspects and medical indications].
• [Intensity modulated radiation therapy].
• A mutant deubiquitinating enzyme (Ubp-M) associates with mitotic chromosomes and blocks cell division.
• [Intensity-modulated radiation therapy for head and neck cancers with bilateral irradiation of the neck : preliminary results].
• Irradiation adaptation to the tumor activity with the help of intensity-modulated radiation therapy for head and neck cancers.
• [Conformal radiotherapy in prostate cancer: for whom and how?].
• [Recommendations for a head and neck IMRT quality assurance protocol].
• [Statistical process control applied to intensity modulated radiotherapy pretreatment controls with portal dosimetry].
• [Preliminary results of the assessment of intensity modulated radiotherapy (IMRT) for prostatic and head and neck tumors (STIC 2001)].
• Impact of intensity-modulated radiotherapy on health-related quality of life for head and neck cancer patients: matched-pair comparison with conventional radiotherapy.
• Qualitative estimation of pelvic organ interactions and their consequences on prostate motion: study on a deceased person.
• A comprehensive analysis of the IMRT dose delivery process using statistical process control (SPC).

Schools

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• Yale University

Doctors Specialties

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• Pathology

Accepted Insurances

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Awards

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• Elected Member

Education

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• Washington University - Barnes-Jewish Hospital
• Yale University School of Medicine

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